Current Opinion in Hematology volume 18, issue 5, P330-337 2011 DOI: 10.1097/moh.0b013e3283497ed5 View full text
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Zhi-Jian Liu, Martha Sola-Visner

Abstract: A better characterization of the molecular differences between fetal/neonatal and adult megakaryocytes is critical to elucidating the pathogenesis of a group of disorders that selectively affect fetal/neonatal megakaryocyte progenitors, including the thrombocytopenia-absent radius (TAR) syndrome, Down syndrome-TMD or Down syndrome-AMKL, and the delayed platelet engraftment following cord blood transplantation.