Abstract:AimWe report the short/mid‐term results of surgery for high‐risk locally advanced rectal cancer (LARC) after neoadjuvant chemotherapy (NAC, four courses of S‐1 + oxaliplatin+ bevacizumab) without radiotherapy with the primary aim of ypT0‐2.MethodsHigh‐risk LARC was defined as cT4b, mesorectal fascia (MRF) ≤1 mm (MRF+), or lateral lymph node metastasis (cLLN+) on high‐resolution MRI. The planned 32 cases from April 2018 to December 2021 were all included.ResultsThere were 10 patients at cT4b (31.2%), 26 MRF+ (8… Show more
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