Abstract:Background. To control advanced cervical squamous cell carcinoma more effectively and more easily, we used neoadjuvant chemotherapy, with three drugs carboplatin, ifosfamide, and peplomycin (PIP), in a study performed from July 1990 to October 1994 in nine Institutions. Methods. Sixty-five patients with untreated, inoperable squamous cell carcinoma of the cervix were treated with carboplatin (300 mg/m 2 IV; low-dose PIP regimen, or T. Nagano ( ) · 400 mg/m 2 IV; high-dose PIP regimen) on day 1, ifosfamide (100… Show more
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