2013
DOI: 10.1590/s0004-28032013000200016
View full text |Buy / Rent full text
|
Sign up to set email alerts
|

Abstract: Radiotherapy and chemotherapy neoadjuvants in patients with squamous cell carcinoma of the esophagus offers benefits and increases survival.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
6
0
1

Year Published

2017
2017
2021
2021

Publication Types

Select...
3

Relationship

2
1

Authors

Journals

citations
Cited by 7 publications
(26 citation statements)
references
References 25 publications
(26 reference statements)
0
6
0
1
Order By: Relevance
“…Several recent publications assess the role of neoadjuvant therapy in squamous cell carcinoma 2 , 17 , 20 , 36 , 39 , 44 , 47 , regarding the disease-free interval and survival. The PET-CT has been suggested as a method for this assessment, still with inconclusive results 2 , 17 , 20 , 36 , 39 , 44 , 47 . However, doubts on the benefits for global survival of patients still persist 14 , 35 , 45 .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Several recent publications assess the role of neoadjuvant therapy in squamous cell carcinoma 2 , 17 , 20 , 36 , 39 , 44 , 47 , regarding the disease-free interval and survival. The PET-CT has been suggested as a method for this assessment, still with inconclusive results 2 , 17 , 20 , 36 , 39 , 44 , 47 . However, doubts on the benefits for global survival of patients still persist 14 , 35 , 45 .…”
Section: Discussionmentioning
confidence: 99%
“…The responders might show complete or incomplete response. The tumoral complete pathologic response to the neoadjuvant therapy is determined by the absence of tumoral cells in the post-esophagectomy specimen, which is a good prognostic factor in the treatment of esophageal cancer 2 , 8 , 38 , 44 .…”
Section: Introductionmentioning
confidence: 99%
“…According to Andreollo et al (2013), in a study with 123 patients that had esophageal cancer and underwent esophagectomy, those who underwent neoadjuvant chemotherapy or radiotherapy had higher survival than those who only underwent surgical treatment. In this study, 37.7% of patients with gastrointestinal cancer had some kind of pre-operative treatment.…”
Section: Discussionmentioning
confidence: 99%
“…In the past, radiotherapy was used as the only form of treatment for squamous cell carcinoma, demonstrating in some studies, results similar to those of surgery. Recently, chemotherapy and associated radiotherapy have shown better survival results, while radiotherapy as the definitive modality has been reserved for patients who cannot receive chemotherapy 1,2,3,9,10,13,14,22,23 .…”
Section: Introductionmentioning
confidence: 99%
“…The inclusion of systemic chemotherapy in the treatment regimens with multimodality, to control distant micrometastatic disease and improve the effects of local radiation through its radiosensitizing effect, made this practice routine, with the main objective of achieving cytoreduction and decreased staging (downstage) 16,22 . Another advantage of neoadjuvant is the fact that cytoreduction and the consequent tumor reduction, the patient eats better, gains weight and acquires a more appropriate nutritional status for a possible surgical procedure, in addition to improving the quality of life due to the lower rate of dysphagia 1,3,24,26 .…”
Section: Introductionmentioning
confidence: 99%