Negative Pressure Wound Therapy With Low Pressure and Gauze Dressings to Treat Diabetic Foot Wounds

Lavery, Lawrence A.; Murdoch, Douglas P.; Kim, Paul J.; Fontaine, Javier La; Thakral, Gaurav; Davis, Kathryn E.

doi:10.1177/1932296813519012

Cited by 17 publications

(7 citation statements)

References 10 publications

(14 reference statements)

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“…Prior clinical studies support the need for robust prospective head to head trials comparing different treatment modalities and techniques in wound care [1,2,25,26]. Combined with the recent prospective study that the results of our economic analysis are based upon, NPWT as a modality is a promising treatment for diabetic foot ulcers [9].…”

Section: Discussionmentioning

confidence: 87%

Cost-minimization analysis of negative pressure wound therapy technologies for the treatment of moderate-to-severe foot infections

et al. 2020

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Aim: The objective was to estimate the cost of care associated with two negative pressure wound therapy (NPWT) technologies used to treat patients admitted to the hospital with moderate-to-severe foot infections. Materials & methods: A decision tree simulation model was developed to estimate the hospital costs associated with two different NPWT technologies: Cardinal Health™ PRO (NPWT-C) and V.A.C. ULTA™ (NPWT-K). Clinical data were obtained from a previously completed single-site prospective trial. One-way and probabilistic sensitivity analyses were performed to gauge the robustness of the results. Results: The total expected per-patient costs were US$41,206 (SD: US$8,194) for NPWT-C and US$44,439 (SD: US$8,963) for NPWT-K. Conclusion: This study found that NPWT-C was expected to minimize the total costs over the episode of treatment. Larger and more clinically diverse studies are recommended to confirm these findings.

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Section: Discussionmentioning

confidence: 87%

Cost-minimization analysis of negative pressure wound therapy technologies for the treatment of moderate-to-severe foot infections

et al. 2020

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“…In this case, it could be useful to apply a low pressure to avoid an impairment of local ischemia. Further, in a recent paper, Lavery reported a high rate of wound closure also with low pressure in the treatment of DF wounds [41] . In our experience, in the case of non-optimal peripheral perfusion, we use a low pressure (75 mmHg) if we have a TcPO2 < 40 mmHg and a higher pressure (100-125 mmHg) if TcPO2 is > 40 mmHg.…”

Section: Indications and Contraindicationmentioning

confidence: 97%

Management of negative pressure wound therapy in the treatment of diabetic foot ulcers

Meloni

Izzo

Vainieri

et al. 2015

WJO

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Diabetic foot (DF) is a common complication of diabetes and the first cause of hospital admission in diabetic patients. In recent years several guidelines have been proposed to reinforce the the management of DF with a notable increase in diabetes knowledge and an overall reduction of amputations. Significant improvements have been reached in the treatment of diabetic foot ulcers (DFUs) and nowadays clinicians have several advanced medications to apply for the best local therapy. Among these, negative pressure wound therapy (NPWT) is a useful adjunct in the management of chronic and complex wounds to promote healing and wound bed preparation for surgical procedures such as skin grafts and flap surgery. NPWT has shown remarkable results although its mechanisms of action are not completely understood. In this paper, we offer a complete overview of this medication and its implication in the clinical setting. We have examined literature related to NPWT concerning human, animal and in vitro studies, and we have summarized why, when and how we can use NPWT to treat DFUs. Further we have associated our clinical experience to scientific evidence in the field of diabetic foot to identify a defined strategy that could guide clinician in the use of NPWT approaching to DFUs. Core tip: This paper represents a summary of the mechanism of action of negative pressure wound therapy and its effectiveness. Further, according to scientific findings and our experience, we propose a flow chart about its use addressed to the field of diabetic foot.Meloni M, Izzo V, Vainieri E, Giurato L, Ruotolo V, Uccioli L. Management of negative pressure wound therapy in the treatment of diabetic foot ulcers.

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“…Parameter settings Pressure For diabetic foot ulcers without vascular lesions, the recommended pressure range is between −125 and −80 mmHg [ 59 , 60 ]. For vascular stenotic or occlusive lesions, the recommended pressure range is between −80 mmHg and −60 mmHg [ 61 ].…”

Section: Recommendationsmentioning

confidence: 99%

Consensus on the application of negative pressure wound therapy of diabetic foot wounds

Ji¹,

Liu²,

Huang³

et al. 2021

Burns &Amp; Trauma

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Because China is becoming an aging society, the incidence of diabetes and diabetic foot have been increasing. Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates. Negative pressure wound therapy (NPWT) is one of the most effective techniques for the treatment of diabetic foot wounds and great progress, both in terms of research and its clinical application, has been made in the last 20 years of its development. However, due to the complex pathogenesis and management of diabetic foot, irregular application of NPWT often leads to complications, such as infection, bleeding and necrosis, that seriously affect its treatment outcomes. In 2020, under the leadership of Burns, Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association, the writing group for ‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’ was established with the participation of scholars from the specialized areas of burns, endocrinology, vascular surgery, orthopedics and wound repair. Drawing on evidence-based practice suggested by the latest clinical research, this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot. The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot.

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Negative Pressure Wound Therapy With Low Pressure and Gauze Dressings to Treat Diabetic Foot Wounds

Cited by 17 publications

References 10 publications

Cost-minimization analysis of negative pressure wound therapy technologies for the treatment of moderate-to-severe foot infections

Cost-minimization analysis of negative pressure wound therapy technologies for the treatment of moderate-to-severe foot infections

Management of negative pressure wound therapy in the treatment of diabetic foot ulcers

Consensus on the application of negative pressure wound therapy of diabetic foot wounds

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