2002
DOI: 10.1001/archderm.138.7.893
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Necrotizing Fasciitis

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Cited by 146 publications
(39 citation statements)
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“…The diagnosis of NF in its early stages is not always possible and can be confused with simple skin infections such as cellulitis [17]. The most common sites for NF are the abdomen, upper limbs, lower limbs, and perineum [18].…”
Section: Introductionmentioning
confidence: 99%
“…The diagnosis of NF in its early stages is not always possible and can be confused with simple skin infections such as cellulitis [17]. The most common sites for NF are the abdomen, upper limbs, lower limbs, and perineum [18].…”
Section: Introductionmentioning
confidence: 99%
“…For the pediatric patient cohort, type 2 infections seem to be more frequent 2. Knowing the possible pathogens, patients should receive broad-spectrum IV antibiotics to cover streptococci, staphylococci, gram negative rods, and anaerobes 8. Clindamycin should be considered since it can switch off exotoxin production and inhibit M protein synthesis, thus promoting phagocytosis and suppressing the effects of bacterial toxins in mediating septic shock 9.…”
Section: Discussionmentioning
confidence: 99%
“…In 2001, Johnston et al 10 presented 7 cases of NF associated with chemotherapy-induced neutropenia treated with broad-spectrum intravenous antibiotics, urgent surgical intervention and HOT therapy. In 2002, Fustes-Morales et al 11 reported 39 children with NF treated with HOT as adjuvant therapy. Just 3 of 39 had ALL as underlying factor.…”
Section: Discussionmentioning
confidence: 99%
“…311 To date, standard regimens, used for adults for the treatment of various diseases, are not available in children and it is fairly obvious that every child requires an individualized treatment. Therefore, the application of HOT therapy in this age group requires, beside the knowledge of the basic principles that regulate HOT, also a close collaboration between the different specialists involved in the care of the child.…”
Section: Introductionmentioning
confidence: 99%