Necrobiosis Lipoidica and Granuloma Annulare

Granuloma Annulare Mimicking Sarcoidosis

“…5 The epithelioid nodule pattern of granuloma annulare is not common. 20 However, all of the biopsies from their study having "small areas with a tuberculoid or sarcoid architecture" were diagnosed as necrobiosis lipoidica. 17 However, in addition to noncaseating granulomas of epitheloid histiocytes containing homogeneous cytoplasm without surrounding inflammation, the absence of asteroid or other giant cell inclusions and the presence of increased mucin between collagen bundles suggest the diagnosis of granuloma annulare.…”

“…4 Indeed, the pathologic features are nearly identical to those observed in lesions of cutaneous sarcoidosis. 20 Nearly a quarter century later, in a study of 14 patients with necrobiosis lipoidica, Gray et al 18 Ackerman 17 included a photomicrograph of "granuloma annulare with sarcoidal features" as an "unusual histologic variant of granuloma annulare (that) resembles sarcoidosis by formation of 'naked' epithelioid tubercules" in the first edition of seminal dermatopathology textbook published in 1978. 1,4 One group of investigators found areas of an infiltrative pattern around the epithelioid nodules 4 ; yet, this is not usually observed.…”

A Variant of Rheumatoid Arthritis resembling Palindromic Rheumatism

“…(Goldberg, 1943) to 30 per cent. (Ellis and Kirby Smith, 1942) of patients with this lesion are not diabetic, the distinction, both clinical and pathological, if it is a real one,. may be difficult.…”

Granuloma annulare and sarcoidosis

“…On reviewing 207 cases of GA (Umbert & Winkelmann, 1977), we observed 7 cases with epithelioid nodules in the skin biopsy. Ellis & Kirby-Smith (1942) documented that a sarcoidal picture could be observed in GA. This is similar to the findings in the current study, in which review of sarcoidosis showed GA patterns.…”