Near-infrared light-triggered drug release from a multiple lipid carrier complex using an all-in-one strategy

Li, Huipeng; Yang, Xue; Zhou, Zhanwei; Wang, Kaikai; Li, Chenzi; Qiao, Hongzhi; Oupický, David; Sun, Minjie

doi:10.1016/j.jconrel.2017.06.029

Cited by 62 publications

(38 citation statements)

References 45 publications

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“…The behavior of light‐induced liposome membrane permeability could occur through several possible pathways, including photoinduced oxidation/isomerization/decomposition/crosslinking of membrane components, local heating induced increase of lipid motions and thus membrane permeabilities, etc . It was demonstrated that NIR light (808 nm, 1 W cm −2 , 4 min) irradiation of a hydrophobic IR780 dye and hydrophilic anti‐metastatic drug AMD3100 coloaded liposome results in release of AMD3100, which then binds the chemokine receptor 4 (CXCR4) receptor of cancer cell membrane, leading to effective inhibition of cancer cell migration and metastasis . CXCR4 is known to be able to inhibit migration and metastasis of breast cancer cells.…”

Section: Photodynamic Therapymentioning

confidence: 99%

Near‐Infrared‐Light‐Activatable Nanomaterial‐Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment

2018

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Cancer is one of the most deadly diseases threatening the lives of humans. Although many treatment methods have been developed to tackle cancer, each modality of cancer treatment has its own limitations and drawbacks. The development of minimally invasive treatment modalities for cancers remains a great challenge. Near-infrared (NIR) light-activated nanomaterial-mediated phototherapies, including photothermal and photodynamic therapies, provide an alternative means for spatially and temporally controlled minimally invasive treatments of cancers. Nanomaterials can serve as nanocargoes for the delivery of chemo-drugs, diagnostic contrast reagents, and organic photosensitizers, and can be used to directly generate heat or reactive oxygen species for the treatment of tumors without the need for organic photosensitizers with NIR-light irradiation. Here, current progress in NIR-light-activated nanomaterial-mediated photothermal therapy and photodynamic therapy is summarized. Furthermore, the effects of size, shape, and surface functionalities of nanomaterials on intracellular uptake, macrophage clearance, biodistribution, cytotoxicities, and biomedical efficacies are discussed. The use of various types of nanomaterials, such as gold nanoparticles, carbon nanotubes, graphene, and many other inorganic nanostructures, in combination with diagnostic and therapeutic modalities for solid tumors, is briefly reviewed.

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Section: Photodynamic Therapymentioning

confidence: 99%

Near‐Infrared‐Light‐Activatable Nanomaterial‐Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment

2018

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“…These nanoparticles were typically formed by the physical addition of small molecular CXCR4 inhibitor like AMD3100 to the formulation. AMD3100 can act as both cancer targeting ligand for improved nanoparticles delivery and CXCR4 antagonism for cancer therapy (Li, Yang, et al, ; Liu et al, ; Zhang et al, ). Chen's group reported a series of CXCR4‐targeted nanoparticles with the ability to deliver both functional siRNA and small drugs for the treatment of liver cancer and liver fibrosis (Gao et al, ; Liu et al, ; Sung et al, ).…”

Section: Cxcr4‐targeted Nanoparticlesmentioning

confidence: 99%

Promise of chemokine network‐targeted nanoparticles in combination nucleic acid therapies of metastatic cancer

Xie

Wang

et al. 2018

WIREs Nanomed Nanobiotechnol

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Chemokines and chemokine receptors play key roles in cancer progression and metastasis. Although multiple chemokines and chemokine receptors have been investigated, inhibition of CXCR4 emerged as one of the most promising approaches in combination cancer therapy, especially when focused on the metastatic disease. Small RNA molecules, such as small interfering RNA (siRNA) and microRNA (miRNA), represent new class of therapeutics for cancer treatment through RNA interference-mediated gene silencing. However, the clinical applicability of siRNA and miRNA is severely limited by the lack of effective delivery systems. There is a significant therapeutic potential for CXCR4-targeted nanomedicines in combination with the delivery of siRNA and miRNA in cancer. Recently developed CXCR4-targeted polymeric drugs and nanomedicines, including cyclam- and chloroquine-based polymeric CXCR4 antagonists are introduced here and their ability to deliver functional siRNA and miRNA is discussed. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease Nanotechnology Approaches to Biology > Nanoscale Systems in Biology.

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“…IR780 iodide, which converts NIR (750-1000 nm) laser energy into heat aer irradiation, is a lipophilic heptamethine NIR absorber with a characteristic absorption peak at 780 nm. [24][25][26][27] It was found to have extraordinary intrinsic tumor targeting properties without further modication. 28 However, IR780 iodide has several limitations, including poor aqueous stability and photostability, which may severely impede its further clinical applications.…”

Section: Introductionmentioning

confidence: 99%

“…28 However, IR780 iodide has several limitations, including poor aqueous stability and photostability, which may severely impede its further clinical applications. 24,29,30 Additionally, the toxicity of IR780 cannot be ignored because of its maximum tolerable dose of 1.5 mg kg À1 in mice. 26,31 To overcome these limitations, some investigators have encapsulated IR780 iodide in various nanoparticles (NPs).…”

Section: Introductionmentioning

confidence: 99%

Near-infrared-induced IR780-loaded PLGA nanoparticles for photothermal therapy to treat breast cancer metastasis in bones

Jiang

et al. 2019

RSC Adv.

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Near-infrared light-triggered drug release from a multiple lipid carrier complex using an all-in-one strategy

Cited by 62 publications

References 45 publications

Near‐Infrared‐Light‐Activatable Nanomaterial‐Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment

Near‐Infrared‐Light‐Activatable Nanomaterial‐Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment

Promise of chemokine network‐targeted nanoparticles in combination nucleic acid therapies of metastatic cancer

Near-infrared-induced IR780-loaded PLGA nanoparticles for photothermal therapy to treat breast cancer metastasis in bones

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