1996
DOI: 10.1016/0735-1097(95)00431-9 View full text |Buy / Rent full text
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Abstract: The presence of severe atherosclerotic disease of the thoracic aorta as defined by transesophageal echocardiography is associated with a high mortality rate. Although the morphologic natural history of the disease process itself is marked by stability over a 1-year period, individual lesion morphology is dynamic, with formation and resolution of mobile components occurring frequently over the same period. The dynamic nature of individual lesion morphology potentially enhances the possibility of developing a su… Show more

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“…9 -11 Nonetheless, these studies did not report regression of carotid atheroma and did not assess risk factors associated with atheroma progression. The rate of regression of AA atheroma noted on TEE in the present study (14%) is similar to that reported in the initial TEE series (10%) 25 but is lower than that reported in patients taking statins. 26 Newer imaging modalities, including MRI, multidetector computed tomography, and electron-beam computed tomography, have been shown to be promising approaches to measure AA progression.…”
Section: Discussionsupporting
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“…9 -11 Nonetheless, these studies did not report regression of carotid atheroma and did not assess risk factors associated with atheroma progression. The rate of regression of AA atheroma noted on TEE in the present study (14%) is similar to that reported in the initial TEE series (10%) 25 but is lower than that reported in patients taking statins. 26 Newer imaging modalities, including MRI, multidetector computed tomography, and electron-beam computed tomography, have been shown to be promising approaches to measure AA progression.…”
Section: Discussionsupporting
“…Over a mean of 1 year, progression was reported in 23% and regression in 10%. 25 In a small group of 16 patients with familial hypercholesterolemia taking pravastatin, Pistavos et al, 26 using monoplanar TEE, noted a rate of progression of 19% and a rate of regression of 38% over 2 years. More recently Geraci and Weinberger, 27 using supraclavicular B-mode ultrasonography of the proximal AA in 89 patients evaluated for transient neurological symptoms, noted a progression rate of 19% and a regression rate of 18% over a mean of 7.7 months (range 3 to 18 months).…”
Section: Discussionmentioning
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“…In addition, mobile lesions in the aorta seen on TEE in 6 patients were seen to be thrombi on surgical pathology. 47 A TEE study 48 showed changes in morphology when TEE was repeated in the same patients over a period of time. New mobile lesions were seen on plaques that initially had none, and some of the presumed thrombi had disappeared (dissolved or embolized) by the time that the repeat study was performed.…”
Section: Pathological Correlationsmentioning
“…The peak LAA flow velocity was determined by pulsewave Doppler echocardiographic interrogation at the orifice of the appendage. The severity of aortic atherosclerosis was evaluated using the grading system of Montgomery et al: 11 grade I=no disease or intimal thickening; grade II=intimal thickening; grade III=atheroma <5 mm; grade IV=atheroma ≥5 mm; and grade V=any mobile atheroma. In the present study, TEE risk was defined as positive when at least one of the following 4 conditions was met: 8 LAA flow velocity <20 cm/s, presence of thrombus, LASEC severity=3 or 4, and aortic atherosclerotic grade=V.…”
Section: Hyperuricemia and Transesophageal Echocardiographicmentioning