National Survey Assessing Treatment ofHelicobacter pyloriInfection in Korean Children: A Pilot Study

Abstract

Background/Aims: The standard guideline for the management Helicobacter pylori infection in Korean children is not present until now. In present study, we conducted the questionnaire survey to investigate the real situation of H. pylori eradication in children. Materials and Methods: Questionnaire concerning the indications of H. pylori eradication, the first choice of treatment modality, the decision method of eradication result, experience of eradication failure, the second choice of treatment modality was sent to doctors who are members of the Korean Society for Pediatric Gastorenterology, Hepatology, and Nutrition. Results: A total of 28 doctors (90.3%) answered the questionnaires among 31 doctors. The most common indication for eradication of H. pylori was peptic ulcer (n=24) followed by chronic abdominal pain (n=17) and positive family history of gastric cancer (n=12). The most common choice of first-line eradication therapy was omeprazole, amoxicillin, clarithromycin triple therapy (n=21) and followed by bismuth subsalicylate, amoxicillin, metronidazole, clarithromycin quadruple therapy (n=7). The results of treatment were judged by C 13 -urea breath test after 2 months later in 19 doctors (67.8%). Twenty four (85.7%) out of 28 doctors had experienced treatment failure. The most common second-line therapy was the sequential therapy (58.3%, 14 doctors among 24). Conclusions: This was the first study for the survey of the treatment of H. pylori infection to Korean pediatricians. The results of this study showed that most pediatric gastroenterologists used to treat H. pylori infection according to the textbook and the com-

Changes in the Treatment Strategies forHelicobacter pyloriInfection in Children and Adolescents in Korea

“…A national survey on the state of H. pylori eradication therapy in children among doctors who were members of the Korean Society for Pediatric Gastroenterology, Hepatology, and Nutrition in 2016 revealed that the most commonly used first-line eradication therapies were PPI-CLA-based triple therapy (75%) and BIS-based quadruple (AMO) therapy (25%). Most pediatric gastroenterologists had experienced treatment failures, and they frequently chose sequential therapy for rescue therapy [28]. Treatment regimens or eradication rates were not different from those of previous studies.…”

Recent Changes in the Treatment of Helicobacter pylori Infection in Children and Adolescents

“…5 10 복통이나 위장관 출혈 등으로 병원에 오는 소아청소년에게 내시경을 시행하면 H. pylori 감염이 확 인되는 경우를 임상에서 흔히 만나게 된다. 소아청소년에서 H. pylori 감염이 확인되면 제균 치료를 해야 하는지, 한다면 어떤 제균 치료를 해야 할지 의사로서 고민을 할 수 있다.…”