N. C. Daw, J. A. Wilimas, W. C. Wang, G. J. Presbury, R. E. Joyner, S. C. Harris, Y. Davis, G. Chen, P. J. Chesney
ABSTRACT. Objective. We studied the prevalence of nasopharyngeal (NP) carriage, antimicrobial susceptibilities, and serotypes of Streptococcus pneumoniae (SP) in children with sickle cell disease (SCD) in the Mid-South. In addition, we examined risk factors for NP carriage of penicillin-resistant SP (PRSP).Study Design. Between July 1994 and December 1995, we obtained NP cultures from 312 children with SCD followed at the Mid-South Sickle Cell Center, 208 (67%) of whom were receiving penicillin prophylaxis.Re…
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