Nanotheranostics-Based Imaging for Cancer Treatment Monitoring

Miao, Tianxin; Oldinski, Rachael A.; Liu, Gang; Chen, Xiaoyuan

doi:10.1007/978-3-030-01775-0_16

Cited by 5 publications

(1 citation statement)

References 153 publications

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“…From the mid-1990s, nanotechnology has been used in therapeutics to target cancer and since then, nanoparticle-based platforms have gradually increased their complexity and have approached a wider range of diseases and conditions [ 35 ]. Nonetheless, due to their increased complexity, theranostic platforms are to date unavailable for clinical use [ 35 , 36 ]. Despite the great performance showed by many of the developed theranostic nanostructures at a preclinical level, only a few nanomaterials have been evaluated in clinical trials [ 37 ].…”

Section: Graphene-based Magnetic Nanoparticles For Theranosticsmentioning

confidence: 99%

Graphene-Based Magnetic Nanoparticles for Theranostics: An Overview for Their Potential in Clinical Application

et al. 2021

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The combination of diagnostics and therapy (theranostic) is one of the most complex, yet promising strategies envisioned for nanoengineered multifunctional systems in nanomedicine. From the various multimodal nanosystems proposed, a number of works have established the potential of Graphene-based Magnetic Nanoparticles (GbMNPs) as theranostic platforms. This magnetic nanosystem combines the excellent magnetic performance of magnetic nanoparticles with the unique properties of graphene-based materials, such as large surface area for functionalization, high charge carrier mobility and high chemical and thermal stability. This hybrid nanosystems aims toward a synergistic theranostic effect. Here, we focus on the most recent developments in GbMNPs for theranostic applications. Particular attention is given to the synergistic effect of these composites, as well as to the limitations and possible future directions towards a potential clinical application.

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