Nanoestructuras De Silicio en Biomedicina Y Biotecnología

Abstract

Silicon nanostructures have properties that make them appealing for applications in biomedicine and biotechnology. The fabrication and characterization of silicon nanostructures are currently gaining a lot of attention and they can include nano-wires, whiskers, pillars, tubes, cones, particles, etc. There are several methods to assist the generation of these nanostructures like laser ablation, thermal evaporation decomposition, and chemical vapor deposition, among others. We consider they are highly potential tools for the improving of diagnosis techniques and the treatment of important biological conditions. The objective of this review is to summarize the main aspects of the physicochemical design of silicon nanomaterials, in addition to toxicological considerations regarding biocompatibility, biodistribution and cell dynamics. Finally, we emphasis on important biomedical applications, such as gene therapy, drug delivery, imaging and sensoring.

A Novel In Situ Sol-Gel Synthesis Method for PDMS Composites Reinforced with Silica Nanoparticles

“…The in situ formation of nanocomposite systems using substrates such as polydimethylsiloxane (PDMS) and metal oxide nanoparticles has presented significant advantages for the development of superhydrophobic surfaces [ 16 ], antimicrobial properties [ 17 ], fouling prevention [ 8 ], and insulating coatings [ 18 ]. The use of silica nanoparticles (SiO 2 ) is particularly noteworthy in this context, where modifications in optical, mechanical, electrical, and chemical properties are achieved based on their size, surface chemistry, and porosity degree, which are adaptable during synthesis and under certain conditions [ 19 ].…”