Nano‐based methods for novel coronavirus 2019 (2019‐nCoV) diagnosis: A review

Abstract

Today, tremendous attention has been devoted to a new coronavirus, SARS‐CoV‐2 (2019‐nCoV), due to severe effects on the global public in all over the world. Rapid and accurate diagnosis of 2019‐nCoV are important for early treatment and cutting off epidemic transmission. In this regard, laboratory detection protocols, such as polymerase chain reaction (PCR) and computed tomography (CT) examination, have been utilized broadly for 2019‐nCoV detection. Recently, nano‐based methods for 2019‐nCoV diagnoses are rapidly expanding and declaring comparable results with PCR and CT. In this review, recent advances in nano‐based techniques have been highlighted and compared briefly with PCR and CT as well‐known methods for 2019‐nCoV detection.

The effects of silver and copper nanoparticles and selenium on Salmo trutta hatchlings

“…It incorporates into its methodology the use of metallic NPs or nanostructures in order to improve PCR efficiency (Yuce et al, 2014). This method is widely used in detection methods in the fields of virology (SARS-CoV-2, gene mutations), as well as in parasitology (waterborne parasites) (Gabriel et al, 2018;Rahimkhoei et al, 2021;Xue et al, 2021). The increase of concentration of amplified genomic fish DNA by gold NPs (Jeong et al, 2015) suggests that other NPs, such as F I G U R E 1 Electrophoretic analysis of 1 μl of Salmo trutta DNA isolates incubated in selenium, silver, and copper solutions at different concentrations.…”

Using an untargeted metabolomics approach to analyze serum metabolites in COVID-19 patients with nucleic acid turning negative

“…The acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused a major threat to worldwide public health, and the new kind of coronavirus pneumonia (COVID-19), an acute respiratory infectious disease, is caused by this infection ( Rahimkhoei et al, 2021 ). According to the World Health Organization, over 435 million cases and 5.9 million fatalities have been reported worldwide as of 1 March 2022 ( WHO 2022 ).…”