Naloxone for opiate-exposed newborn infants

Psychosocial, pharmacological, and legal interventions for improving the psychosocial outcomes of children with substance misusing parents: A systematic review

“…Across the existing body of reviews, authors frequently highlight the limited amount of high‐quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Bröning et al, 2012; Calhoun et al, 2015; McGovern et al, 2021; Krahn et al, 2018; Moe et al, 2013; Turnbull & Osborn, 2012; Zhang et al, 2018). Reviews with less systematic methodologies and/or without meta‐analyses range from concluding that existing interventions show promise for improving child outcomes (e.g., McCalman et al, 2017; MacVicar et al, 2019; Niccols et al, 2012; Templeton et al, 2010) to concluding that here is insufficient evidence to ascertain effectiveness (e.g., Bowie, 2005; Peisch et al, 2018; Ritland et al, 2020; West et al, 2020).…”

“…Across the existing body of reviews, authors frequently highlight the limited amount of high-quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Calhoun et al, 2015;McGovern et al, 2021;Krahn et al, 2018;Moe et al, 2013;Turnbull & Osborn, 2012;.…”

Psychosocial, pharmacological, and legal interventions for improving the psychosocial outcomes of children with substance misusing parents: A systematic review

“…Across the existing body of reviews, authors frequently highlight the limited amount of high‐quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Bröning et al, 2012; Calhoun et al, 2015; McGovern et al, 2021; Krahn et al, 2018; Moe et al, 2013; Turnbull & Osborn, 2012; Zhang et al, 2018). Reviews with less systematic methodologies and/or without meta‐analyses range from concluding that existing interventions show promise for improving child outcomes (e.g., McCalman et al, 2017; MacVicar et al, 2019; Niccols et al, 2012; Templeton et al, 2010) to concluding that here is insufficient evidence to ascertain effectiveness (e.g., Bowie, 2005; Peisch et al, 2018; Ritland et al, 2020; West et al, 2020).…”

“…Across the existing body of reviews, authors frequently highlight the limited amount of high-quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Calhoun et al, 2015;McGovern et al, 2021;Krahn et al, 2018;Moe et al, 2013;Turnbull & Osborn, 2012;.…”

Singapore Neonatal Resuscitation Guidelines 2016

“…Animal studies and case reports highlighted complications such as pulmonary oedema, cardiac arrest and seizures with the use of naloxone. (122,123) …”

The ethics of neonatal research: A trialists' perspective

“…[29] Does naloxone reduce risk of intensive care admission or improve breast feeding in infants exposed in utero to opiates? [30] NDI, neurodevelopmental impairment; ECMO, extracorporeal membrane oxygenation.…”

Psychosocial, pharmacological, and legal interventions for improving the psychosocial outcomes of children with substance misusing parents: A systematic review

“…Across the existing body of reviews, authors frequently highlight the limited amount of high‐quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Bröning et al, 2012; Calhoun et al, 2015; McGovern et al, 2021; Krahn et al, 2018; Moe et al, 2013; Turnbull & Osborn, 2012; Zhang et al, 2018). Reviews with less systematic methodologies and/or without meta‐analyses range from concluding that existing interventions show promise for improving child outcomes (e.g., McCalman et al, 2017; MacVicar et al, 2019; Niccols et al, 2012; Templeton et al, 2010) to concluding that here is insufficient evidence to ascertain effectiveness (e.g., Bowie, 2005; Peisch et al, 2018; Ritland et al, 2020; West et al, 2020).…”

“…Across the existing body of reviews, authors frequently highlight the limited amount of high-quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Calhoun et al, 2015;McGovern et al, 2021;Krahn et al, 2018;Moe et al, 2013;Turnbull & Osborn, 2012;.…”

Singapore Neonatal Resuscitation Guidelines 2016

“…Animal studies and case reports highlighted complications such as pulmonary oedema, cardiac arrest and seizures with the use of naloxone. (122,123) …”

The ethics of neonatal research: A trialists' perspective

“…[29] Does naloxone reduce risk of intensive care admission or improve breast feeding in infants exposed in utero to opiates? [30] NDI, neurodevelopmental impairment; ECMO, extracorporeal membrane oxygenation.…”

Psychosocial, pharmacological, and legal interventions for improving the psychosocial outcomes of children with substance misusing parents: A systematic review

“…Across the existing body of reviews, authors frequently highlight the limited amount of high‐quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Bröning et al, 2012; Calhoun et al, 2015; McGovern et al, 2021; Krahn et al, 2018; Moe et al, 2013; Turnbull & Osborn, 2012; Zhang et al, 2018). Reviews with less systematic methodologies and/or without meta‐analyses range from concluding that existing interventions show promise for improving child outcomes (e.g., McCalman et al, 2017; MacVicar et al, 2019; Niccols et al, 2012; Templeton et al, 2010) to concluding that here is insufficient evidence to ascertain effectiveness (e.g., Bowie, 2005; Peisch et al, 2018; Ritland et al, 2020; West et al, 2020).…”

“…Across the existing body of reviews, authors frequently highlight the limited amount of high-quality evaluation evidence and depending on the research question and synthesis approach, authors have reached varying conclusions about overall effectiveness. More rigorous systematic reviews tend to align with the current review by concluding that the existing evidence limits the ability to draw solid conclusions or find mixed evidence for effectiveness (e.g., Calhoun et al, 2015;McGovern et al, 2021;Krahn et al, 2018;Moe et al, 2013;Turnbull & Osborn, 2012;.…”

Singapore Neonatal Resuscitation Guidelines 2016

“…Animal studies and case reports highlighted complications such as pulmonary oedema, cardiac arrest and seizures with the use of naloxone. (122,123) …”

The ethics of neonatal research: A trialists' perspective

“…[29] Does naloxone reduce risk of intensive care admission or improve breast feeding in infants exposed in utero to opiates? [30] NDI, neurodevelopmental impairment; ECMO, extracorporeal membrane oxygenation.…”