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Abstract

ABSTRACT:In order to improve the water-solubility of curcumin, the complex between curcumin and hyperbranched poly(amide-ester) was formed by dispering the solid curcumin in hyperbranched poly(amide-ester) aqueous solution. The interaction process was characterized by UV-vis absorption spectroscopy, Fluorescence quenching method, Fourier transformation-infrared spectroscopy, thermogravimetric analysis. Fluorescence quenching ananlysis reveal that the fluorescence quenching of curcumin is due to the formation of ground state complex between curcumin and hyperbranched poly(amide-ester) and the binding constant was 3.98×10 5 L·mol -1 . The other analysis also can prove the formation of complex between curcumin and HBPAE. The solubility of curcumin in aqueous solution was greatly increased more than 1000-fold at the presence of hyperbranched poly(amide-ester).