Myoclonic Epilepsy

The Relation Between the Electroencephalogram and Muscle Action Potentials in Certain Convulsive States

“…The results of the investigations described above in the patients with severe myoclonic jerkings confirm the findings of Grinker et al (1938), and in the patient with wave and spike discharge with myoclonus those of Jasper and Andrews, (1938). The present cases of severe myoclonic jerkings show spikelike discharges in the EEG apparently exactly comparable with those described by Grinker et al After discussing their findings Grinker et al decided that the disturbances in myoclonic epilepsy probably had a cortical rather than a subcortical origin.…”

The Relation Between the Electroencephalogram and Muscle Action Potentials in Certain Convulsive States

“…The results of the investigations described above in the patients with severe myoclonic jerkings confirm the findings of Grinker et al (1938), and in the patient with wave and spike discharge with myoclonus those of Jasper and Andrews, (1938). The present cases of severe myoclonic jerkings show spikelike discharges in the EEG apparently exactly comparable with those described by Grinker et al After discussing their findings Grinker et al decided that the disturbances in myoclonic epilepsy probably had a cortical rather than a subcortical origin.…”

Some observations on electroencephalograms of myoclonus epilepsy

“…EEGs of myoclonus epilepsy were reported by previous authors and were described as showing continuous severe generalized slow waves interspersed with spikes, polyspikes, and sharp waves (Grinker et al, 1938;Delay, Fischgold, Pichot, and Verdeaux, 1947;Gastaut and Remond, 1952;Watson and Denny-Brown, 1953;De Ajuriaguerra, Sigwald, and Piot, 1954;Schwarz and Yanoff, 1965). Indeed, EEGs of our second and fourth case showed prominent high-voltage slow waves with or without spikes, but EEGs of the first case at a terminal stage were dominated by a large number of spikes, polyspikes, and sharp waves with less marked slow waves.…”

Diagnostic Utility of Clinical Neurophysiology in Jerky Movement Disorders: A Review from the MDS Clinical Neurophysiology Study Group

“…Professor Friedreich in 1881 12 first published a case of a man affected by pneumonia, who exhibited brief, arrhythmic, stimulus‐sensitive, multifocal twitches that he called paramyoclonus multiplex. Grinker, Serota, and Stein 13 observed that EEG abnormalities were related to specific jerky movements in epileptic patients, and Dawson 14 reported the first recordings of enlarged SEP in patients with myoclonic epilepsy, evoked by tapping tendons or electrical stimulation. Halliday 15 further characterized the cortical involvement in what he called “pyramidal” myoclonus.…”

The Relation Between the Electroencephalogram and Muscle Action Potentials in Certain Convulsive States

“…The results of the investigations described above in the patients with severe myoclonic jerkings confirm the findings of Grinker et al (1938), and in the patient with wave and spike discharge with myoclonus those of Jasper and Andrews, (1938). The present cases of severe myoclonic jerkings show spikelike discharges in the EEG apparently exactly comparable with those described by Grinker et al After discussing their findings Grinker et al decided that the disturbances in myoclonic epilepsy probably had a cortical rather than a subcortical origin.…”

Some observations on electroencephalograms of myoclonus epilepsy

“…EEGs of myoclonus epilepsy were reported by previous authors and were described as showing continuous severe generalized slow waves interspersed with spikes, polyspikes, and sharp waves (Grinker et al, 1938;Delay, Fischgold, Pichot, and Verdeaux, 1947;Gastaut and Remond, 1952;Watson and Denny-Brown, 1953;De Ajuriaguerra, Sigwald, and Piot, 1954;Schwarz and Yanoff, 1965). Indeed, EEGs of our second and fourth case showed prominent high-voltage slow waves with or without spikes, but EEGs of the first case at a terminal stage were dominated by a large number of spikes, polyspikes, and sharp waves with less marked slow waves.…”

Diagnostic Utility of Clinical Neurophysiology in Jerky Movement Disorders: A Review from the MDS Clinical Neurophysiology Study Group

“…Professor Friedreich in 1881 12 first published a case of a man affected by pneumonia, who exhibited brief, arrhythmic, stimulus‐sensitive, multifocal twitches that he called paramyoclonus multiplex. Grinker, Serota, and Stein 13 observed that EEG abnormalities were related to specific jerky movements in epileptic patients, and Dawson 14 reported the first recordings of enlarged SEP in patients with myoclonic epilepsy, evoked by tapping tendons or electrical stimulation. Halliday 15 further characterized the cortical involvement in what he called “pyramidal” myoclonus.…”

The Relation Between the Electroencephalogram and Muscle Action Potentials in Certain Convulsive States

“…The results of the investigations described above in the patients with severe myoclonic jerkings confirm the findings of Grinker et al (1938), and in the patient with wave and spike discharge with myoclonus those of Jasper and Andrews, (1938). The present cases of severe myoclonic jerkings show spikelike discharges in the EEG apparently exactly comparable with those described by Grinker et al After discussing their findings Grinker et al decided that the disturbances in myoclonic epilepsy probably had a cortical rather than a subcortical origin.…”

Some observations on electroencephalograms of myoclonus epilepsy

“…EEGs of myoclonus epilepsy were reported by previous authors and were described as showing continuous severe generalized slow waves interspersed with spikes, polyspikes, and sharp waves (Grinker et al, 1938;Delay, Fischgold, Pichot, and Verdeaux, 1947;Gastaut and Remond, 1952;Watson and Denny-Brown, 1953;De Ajuriaguerra, Sigwald, and Piot, 1954;Schwarz and Yanoff, 1965). Indeed, EEGs of our second and fourth case showed prominent high-voltage slow waves with or without spikes, but EEGs of the first case at a terminal stage were dominated by a large number of spikes, polyspikes, and sharp waves with less marked slow waves.…”

Diagnostic Utility of Clinical Neurophysiology in Jerky Movement Disorders: A Review from the MDS Clinical Neurophysiology Study Group

“…Professor Friedreich in 1881 12 first published a case of a man affected by pneumonia, who exhibited brief, arrhythmic, stimulus‐sensitive, multifocal twitches that he called paramyoclonus multiplex. Grinker, Serota, and Stein 13 observed that EEG abnormalities were related to specific jerky movements in epileptic patients, and Dawson 14 reported the first recordings of enlarged SEP in patients with myoclonic epilepsy, evoked by tapping tendons or electrical stimulation. Halliday 15 further characterized the cortical involvement in what he called “pyramidal” myoclonus.…”