Myeloid Colony-Stimulating Factors

Factors affecting neutrophil and platelet reconstitution following T cell-depleted bone marrow transplantation: differential effects of growth factor type and role of CD34+ cell dose

“…GM-CSF treatment of children, in contrast, seems to cause an elevation in platelet counts (reviewed in Ref. 44). Similar to our findings, G-CSF was shown to have a more pronounced effect in enhancing neutrophil engraftment than GM-CSF when directly compared in the autologous setting.…”

Factors affecting neutrophil and platelet reconstitution following T cell-depleted bone marrow transplantation: differential effects of growth factor type and role of CD34+ cell dose

“…GM-CSF treatment of children, in contrast, seems to cause an elevation in platelet counts (reviewed in Ref. 44). Similar to our findings, G-CSF was shown to have a more pronounced effect in enhancing neutrophil engraftment than GM-CSF when directly compared in the autologous setting.…”

Granulocyte colony-stimulating factor for preterms with sepsis and neutropenia: A randomized controlled trial

“…[12] GCSF therapy in very low birth weight (VLBW) infants was demonstrated to be safe and tolerance is good. [13] Clinical trials in neonates have been preceded by extensive in vitro and animal studies because of the concern about acute and long-term toxicities of such agents in neonates. [10] There is a dearth of studies and clinical trials in this field and there is a pressing need of such studies to establish or to reject the use of GCSF to improve survival in neonatal sepsis.…”

Factors affecting neutrophil and platelet reconstitution following T cell-depleted bone marrow transplantation: differential effects of growth factor type and role of CD34+ cell dose

“…GM-CSF treatment of children, in contrast, seems to cause an elevation in platelet counts (reviewed in Ref. 44). Similar to our findings, G-CSF was shown to have a more pronounced effect in enhancing neutrophil engraftment than GM-CSF when directly compared in the autologous setting.…”

Granulocyte colony-stimulating factor for preterms with sepsis and neutropenia: A randomized controlled trial

“…[12] GCSF therapy in very low birth weight (VLBW) infants was demonstrated to be safe and tolerance is good. [13] Clinical trials in neonates have been preceded by extensive in vitro and animal studies because of the concern about acute and long-term toxicities of such agents in neonates. [10] There is a dearth of studies and clinical trials in this field and there is a pressing need of such studies to establish or to reject the use of GCSF to improve survival in neonatal sepsis.…”

Factors affecting neutrophil and platelet reconstitution following T cell-depleted bone marrow transplantation: differential effects of growth factor type and role of CD34+ cell dose

“…GM-CSF treatment of children, in contrast, seems to cause an elevation in platelet counts (reviewed in Ref. 44). Similar to our findings, G-CSF was shown to have a more pronounced effect in enhancing neutrophil engraftment than GM-CSF when directly compared in the autologous setting.…”

Granulocyte colony-stimulating factor for preterms with sepsis and neutropenia: A randomized controlled trial

“…[12] GCSF therapy in very low birth weight (VLBW) infants was demonstrated to be safe and tolerance is good. [13] Clinical trials in neonates have been preceded by extensive in vitro and animal studies because of the concern about acute and long-term toxicities of such agents in neonates. [10] There is a dearth of studies and clinical trials in this field and there is a pressing need of such studies to establish or to reject the use of GCSF to improve survival in neonatal sepsis.…”