Mycosis fungoides palmaris et plantaris

Resnik, K. S.

doi:10.1001/archderm.131.9.1052

Cited by 20 publications

(25 citation statements)

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“…Though only a fraction of MF patients (4 out of 722) presented with skin lesions that were restricted to or primarily affected the palms and soles, growing awareness will likely help to identify patients with this rare variant otherwise diagnosed or classified as chronic palmoplantar eczema resistant to standard therapy. This assumption is supported by increasing numbers of case reports since the introduction of the term by Resnik et al [2]in 1995 [14, 25, 26, 27, 28, 29]. We report 3 additional patients with MF-type CTCL of the hands and soles, based on indicative and diagnostic histopathology (fig.…”

Section: Discussionsupporting

confidence: 58%

“…In line with this proposed unifying concept, the entity of MF palmaris et plantaris was introduced recently as a distinct variant that groups patients with skin lesions confined to the palms and soles based on clinical and histopathologic MF-like characteristics [2]. Reevaluating the literature, Resnik et al [2]found 12 more patients in addition to their own four cases who were eligible for this diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…Reevaluating the literature, Resnik et al [2]found 12 more patients in addition to their own four cases who were eligible for this diagnosis. Though only a fraction of MF patients (4 out of 722) presented with skin lesions that were restricted to or primarily affected the palms and soles, growing awareness will likely help to identify patients with this rare variant otherwise diagnosed or classified as chronic palmoplantar eczema resistant to standard therapy.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, based on clinical, histologic, immunohistologic, and molecular findings, this subset of CTCL has been coined ‘mycosis fungoides palmaris et plantaris’ [2]. Within the last 2 years, 3 patients referred to our department classified as chronic treatment-refractory eczema were subsequently diagnosed with mycosis fungoides (MF)-type CTCL of the hands and/or soles.…”

Section: Introductionmentioning

confidence: 99%

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Mycosis-fungoides-Type Cutaneous T Cell Lymphoma of the Hands and Soles: A Variant Causing Delay in Diagnosis and Adequate Treatment of Patients with Palmoplantar Eczema

Spieth

Grundmann-Kollmann²,

Runne³

et al. 2002

Dermatology

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Background: The etiopathology of chronic eczematous lesions of the palms and/or soles remains elusive in a considerable proportion of patients. Accumulating evidence suggests that a rare variant of mycosis fungoides (MF)-type cutaneous T cell lymphoma (CTCL) restricted to the palms and/or soles may mimic common palmoplantar dermatoses. Objective: In the present study, we analyzed the clinical and histological characteristics of 3 adult patients with preexisting nonclassified chronic palmoplantar eczema poorly responding to standard therapies. Palmar and/or plantar MF was eventually diagnosed. Methods: The course of the disease, response to previous therapies and dermatological features are described, results of histochemical and immunohistochemical analyses are reported, including T cell receptor γ gene rearrangement where obtainable. Results: Onset of cutaneous lesions with broad clinical variation was experienced 2–10 years prior to diagnosis; conventional therapies led to short-time or partial remission only; except for 1 patient, the epidermotropic infiltrate was predominantly composed of CD4-positive cells; topical photochemotherapy seems to result in more durable responses. Conclusion: As therapeutic strategies for this disease variant differ from symptomatic standard treatment regimens, awareness of MF-type CTCL as a relevant differential diagnosis of palmoplantar eczema should be expanded to prevent delay in diagnosis and adequate therapy.

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Section: Discussionsupporting

confidence: 58%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Mycosis-fungoides-Type Cutaneous T Cell Lymphoma of the Hands and Soles: A Variant Causing Delay in Diagnosis and Adequate Treatment of Patients with Palmoplantar Eczema

Spieth

Grundmann-Kollmann²,

Runne³

et al. 2002

Dermatology

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“…Another controversial aspect of PR is its relationship to MF (5,16,18,(27)(28)(29)(30)(31)(32). Much of the controversy arises from the clinical and microscopic similarities between the two entities, the lack of established diagnostic criteria for PR, and, as a result, different interpretations by different authors.…”

Section: Cd2mentioning

confidence: 99%

Pagetoid Reticulosis (Woringer-Kolopp Disease): An Immunophenotypic, Molecular, and Clinicopathologic Study

et al. 2000

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Pagetoid reticulosis (PR), also known as WoringerKolopp disease, is a form of cutaneous T-cell lymphoma that demonstrates striking epidermotropism on histologic examination. We present the histologic, immunologic, and molecular findings for seven patients who had PR. The patients ranged in age from 33 to 67 years. All patients presented with one or several thick plaques involving the distal extremities except for one patient, who presented with a tongue lesion.

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