Mycosis fungoides associated with dystrophic xanthomatosis

Verruciform xanthoma: Report of five cases

“…Xanthomatous changes in the papillary dermis, similar to that in VX, have been described in association with several diseases, including mycosis fungoides,[17] epithelial nevi,[1819] and dystrophic epidermolysis bullosa. [2021] The changes may histologically resemble true VX and are considered to be a form of dystrophic xanthomatosis that possibly arises due to repeated epidermal or dermal damage, with accumulation of lipids within macrophages.…”

Dystrophic Xanthomatosis in Primary CD30-Positive Cutaneous T-Cell Lymphoma

“…In such instances, they usually corresponded to nodules undergoing degeneration or regression after treatment. Histologically, these lesions are characterized by a diffuse dermal infiltration with lipid-laden macrophages without an evident lymphomatous infiltrate [2, 4, 27, 28, 29, 30, 31, 32]. Only in rare circumstances has xanthomatosis been noted to develop in lesions of CD30+ cutaneous lymphoid proliferations [3, 27, 33].…”