2001
DOI: 10.1590/s0004-282x2001000500005 View full text |Buy / Rent full text
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Abstract: -Myasthenia gravis (MG) in childhood is rare comprising 10 to 20 % of all myasthenic patients. We studied 18 patients with MG whose first symptoms started from 1 to 12 years of age, followed at the Department of Neurology of the UNI.ESP-EPM, from January 1983 to August 1997. There were 10 girls and 8 boys (1.2:1). Eleven patients (61%) presented moderate or severe generalized disease and 4 (22%) had at least one myasthenic crisis. EMG with supramaximal repetitive nerve stimulation was diagnostic in 8 (47%) out… Show more

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“…Two patients had ocular myasthenia and three the generalized form of the disease. As for disease severity in early childhood, this finding is similar to data from Evoli et al and Morita et al who found not only a high frequency of ocular myasthenia but also an even higher incidence of severe disease with respiratory involvement 13,14 .…”
Section: General Socio-demographic Findingssupporting
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“…Two patients had ocular myasthenia and three the generalized form of the disease. As for disease severity in early childhood, this finding is similar to data from Evoli et al and Morita et al who found not only a high frequency of ocular myasthenia but also an even higher incidence of severe disease with respiratory involvement 13,14 .…”
Section: General Socio-demographic Findingssupporting
“…All patients in the group with such early age of onset in the present study were females. Such finding reflects that of a previous analysis of 18 patients under 12 years old, where there was a female predominance in pre-pubertal patients 14 , but another study failed to show differences in gender distribution in prepubertal MG 13 . Two patients had ocular myasthenia and three the generalized form of the disease.…”
Section: General Socio-demographic Findingssupporting
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“…Girls are more commonly affected than boys (1.3 -1.8) 4,5 . In Morita et al, Most of the cases presented between 9 to 12 years of age 6 . Our case was also a female child presented in the early age.…”
Section: Discussionmentioning