volume 11, issue Suppl 1, PP191 2008
DOI: 10.1186/1758-2652-11-s1-p191
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Abstract: Purpose of the studyLopinavir/ritonavir (LPV/r) is increasingly being introduced in resource-limited settings as second-line therapy. Data on selection of resistance mutations (RAMs) in treatment-experienced populations failing LPV/r could provide insight into future ramifications of this strategy. We investigated the RAMs in patients with prior or current LPV/r failure. MethodsWe identified 195 samples from multi-treated patients submitted for routine resistance testing. Seventy-one (36%) never received LPV/…

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