volume 66, issue 7, P4201-4208 1992
DOI: 10.1128/jvi.66.7.4201-4208.1992
View full text
|
Sign up to set email alerts
|
Share

Abstract: Human papillomavirus type 16 (HPV16) E6 and E7 are selectively retained and expressed in HPV16associated human genital tumors. E6 is active in several cell culture assays, including transformation of NIH 3T3 cells, trans activation of the adenovirus E2 promoter, and cooperation with E7 to immortalize normal human keratinocytes. Biochemically, the HPV16 E6 protein has been shown to bind to tumor suppressor protein p53 in vitro and induce its degradation in a rabbit reticulocyte lysate. To examine the relationsh…

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

3
17
0

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals