Multiresistant zoonotic pathogens isolated from goat milk in Northeastern Brazil

Antimicrobial and Methicillin Resistance Pattern of Potential Mastitis-Inducing Staphylococcus aureus and Coagulase-Negative Staphylococci Isolates from the Mammary Secretion of Dairy Goats

“…This easy-to-use, high-throughput and cost-effective technology provides rapid and accurate bacterial identification at genus and species level, rendering it a diagnostic tool with increasing popularity [ 41 ]. CoNS represented the majority of the staphylococcal isolates (72.3%) in agreement with previous studies in Greece [ 10 , 11 ], Italy, Brazil, Portugal and USA [ 16 , 17 , 19 , 20 , 40 ]. S. epidermidis (23.3%) and S. caprae (21.9%) were the dominant species, followed by S. simulans , S. chromogenes (11% each) and S. equorum (8.2%), with the remaining CoNS species being present at <5.5%.…”

“…S. epidermidis (23.3%) and S. caprae (21.9%) were the dominant species, followed by S. simulans , S. chromogenes (11% each) and S. equorum (8.2%), with the remaining CoNS species being present at <5.5%. Most of the CoNS species identified in the current study have also been reported previously in goats with clinical or subclinical mastitis [ 10 , 16 , 17 , 19 , 20 , 40 ]. The variation in the prevalence of each species across studies is probably due to differences in geographic location, management practices and isolation and identification methodologies.…”

“…Taking into account the routine use of β-lactams as mastitis treatment in dairy goats, this practice may facilitate the emergence of methicillin-resistant staphylococci in the produced milk and dairy products [ 15 ]. In several studies, S. aureus and CoNS strains resistant to one or more antimicrobials and even multi-drug resistant (MDR) strains have been isolated from goat milk collected from individual animals with [ 13 , 16 , 17 , 18 ] or without mastitis [ 19 , 20 ], with a high frequency of resistance to various members of the β-lactams groups commonly observed. Concerning the presence of methicillin-resistant S. aureus (MRSA) in goats with clinical/subclinical mastitis, the prevalence of such isolates was generally considered very low based on the detection of mecA and mecC genes [ 12 , 13 , 16 ].…”

“…MRSA strains harboring the mecA gene have also been isolated from milk samples of clinically healthy goats [ 18 ]. Interestingly, methicillin-resistant CoNS (MR-CoNS) have been reported in the milk of goats with [ 17 ] or without mastitis [ 19 ], suggesting that this staphylococcal group should also be considered during the evaluation of methicillin resistance in this animal species. AMR presence in S. aureus and CoNS poses a threat for public health, as the dissemination of resistant bacteria to humans, either due to direct contact with carrier animals or via the consumption of contaminated food, may lead to difficult-to-treat infections and/or the spread of AMR genes to human pathogens [ 21 ].…”

Comparative analysis of caseins in Saanen goat milk from 3 different regions of China using quantitative proteomics

“…Milk is regarded as a high-quality food beneficial to human development (Mirzaei and Chaleshtori, 2021). Goat milk has higher digestibility, better mineral bioavailability, and more balanced protein distribution than cow milk (Chen et al, 2020;Aragão et al, 2021). Goat milk is not prone to allergic reactions and can be used by women and children (Costa et al, 2021).…”