Multiresidue determination of antibiotics in feed and fish samples for food safety evaluation. Comparison of immunoassay vs LC-MS-MS

The combined and second exposure effect of copper (II) and chlortetracycline on fresh water algae, Chlorella pyrenoidosa and Microcystis aeruginosa

“…et al, 2010).Via the transportations among different media in the environment, once released, antibiotics and heavy metals are likely to cause water pollution and affect the aquatic system. The detections of antibiotics have been conducted in various environmental media (Christian T. et al, 2003, Tong L. et al, 2009) as well as organisms (Chafer-Pericas C. et al, 2011). Meanwhile the heavy metals can be released anthropogenically and naturally to the environment, the relatively high concentrations of which have been proved to be biologically harmful (Balamurugan K. et al, 2006).…”

LC/ESI/MS/MS method development and validation for the determination of sulfonamide antibiotic residues in shrimp sample

“…For quantitative analysis, high performance liquid chromatography with fluorescence or mass spectrometric detection are the most widely used techniques. LC-MS/MS is one of the most promising techniques for the analysis of antimicrobials in animal tissues, because it allows drug quantification and confirmation at trace levels [16][17][18][19][20][21][22][23] . In this paper we describe the method development and validation of simple and sensitive LC/MS/MS method and simple sample clean-up process for the determination of nine SAs in shrimp sample the structures of studied sulfonamides are given in the scheme.1.…”

Investigation and monitroing of tetracycline and degradation products in waters of trout farm

“…Antibiotics kill the microorganisms or inhibit the growth of them [12]. A class of antibiotics, tetracyclines (TCs), are characterized by a broad spectrum of activity, a relatively high degree of safety, low production and sales costs [13].…”