volume 1, issue 3, P100107 2020
DOI: 10.1016/j.xpro.2020.100107
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Abstract: Summary This protocol describes a high-throughput and multiplexed DNA fluorescence in situ hybridization method to trace chromosome conformation in Caenorhabditis elegans embryos. This approach generates single-cell and single-chromosome localization data that can be used to determine chromosome conformation and assess the heterogeneity of structures that exist in vivo . This strategy is flexible through modifications to the probe …

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