Multiple Telangiectases of the Brain

Hereditary haemorrhagic telangiectasia: neuropathological observations.

“…Davison and Rosenheck (1937) report a case of mesencephalic telangiectases and discuss the rarity of neurological signs in telangiectasia of the central nervous system. Michael and Levin (1936) on the other hand, report a family with hereditary telangiectasia which caused convulsions and focal neurological signs. In their review of previous cases of telangiectasia, neurological manifestations, often transient, were said to be common.…”

Hereditary haemorrhagic telangiectasia: neuropathological observations.

“…Davison and Rosenheck (1937) report a case of mesencephalic telangiectases and discuss the rarity of neurological signs in telangiectasia of the central nervous system. Michael and Levin (1936) on the other hand, report a family with hereditary telangiectasia which caused convulsions and focal neurological signs. In their review of previous cases of telangiectasia, neurological manifestations, often transient, were said to be common.…”

KRIT1 , a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein

“…Since its initial description, CCM has been recognized to be a heritable disorder (14)(15)(16). Genetic analysis of kindreds with familial CCM has mapped three autosomal dominant loci causing this disease.…”

Hereditary haemorrhagic telangiectasia: neuropathological observations.

“…Davison and Rosenheck (1937) report a case of mesencephalic telangiectases and discuss the rarity of neurological signs in telangiectasia of the central nervous system. Michael and Levin (1936) on the other hand, report a family with hereditary telangiectasia which caused convulsions and focal neurological signs. In their review of previous cases of telangiectasia, neurological manifestations, often transient, were said to be common.…”

KRIT1 , a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein

“…Since its initial description, CCM has been recognized to be a heritable disorder (14)(15)(16). Genetic analysis of kindreds with familial CCM has mapped three autosomal dominant loci causing this disease.…”

Hereditary haemorrhagic telangiectasia: neuropathological observations.

“…Davison and Rosenheck (1937) report a case of mesencephalic telangiectases and discuss the rarity of neurological signs in telangiectasia of the central nervous system. Michael and Levin (1936) on the other hand, report a family with hereditary telangiectasia which caused convulsions and focal neurological signs. In their review of previous cases of telangiectasia, neurological manifestations, often transient, were said to be common.…”

KRIT1 , a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein

“…Since its initial description, CCM has been recognized to be a heritable disorder (14)(15)(16). Genetic analysis of kindreds with familial CCM has mapped three autosomal dominant loci causing this disease.…”