Multiple Splenic Infarcts Complicating Plasmodium vivax Malaria

Tripathi, Neha; Saha, Abhijeet; Kaur, Manpreet

doi:10.1097/pec.0000000000001942

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…Но все эти проявления неспецифические и поставить диагноз без использования методов лучевой визуализации невозможно [5, 12 15]. Основным методом лучевой диагностики инфаркта селезенки является КТ с внутривенным контрастированием, при котором зоны инфаркта выглядят гиподенсными и аваскулярными [6,16].…”

Section: Discussionunclassified

Ultrasonic Diagnostics of Spleen Infarction in a Hematological Patient

Danzanova

Бердников²,

Гудилина³

et al. 2023

jour

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Section: Discussionunclassified

Ultrasonic Diagnostics of Spleen Infarction in a Hematological Patient

Danzanova

Бердников²,

Гудилина³

et al. 2023

jour

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“…Infection Cytomegalovirus [6][7][8] Epstein-Barr virus [9][10][11][12][13][14][15] Infective endocarditis [16][17][18][19][20][21][22] COVID-19 [23][24][25][26][27][28][29][30][31][32][33][34][35] Dengue virus [36] Mycoplasma pneumoniae [37,38] Malaria [39,40] Scrub typhus [41,42] Aspergillus pericarditis [43] Babesiosis [44] Malignancy including neoplasm and myeloproliferative diseases…”

Section: Causes Of Splenic Infarction Referencesmentioning

confidence: 99%

Clinical, Hematological, Biochemical and Radiological Characteristics for Patients With Splenic Infarction: Case Series With Literature Review

et al. 2023

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Background Splenic infarction is a frequently missed diagnosis in acute clinical conditions and is often under-diagnosed due to the lack of high-quality evidence on pathophysiology of splenic infarction. Due to the scarcity of such evidence, no consensus guidelines regarding the diagnostic approach and management of patients with splenic infarction exist. Most of published articles on splenic infarction are case reports and there was no systematic review on splenic infarction. Methods We conducted a retrospective analysis of all radiologically confirmed cases of splenic infarction patients with any history of admission at National Center for Global Health and Medicine Kohnodai Hospital, from 2014 to 2020. Further, to understand the pathophysiology that causes splenic infarction, we searched the literatures on splenic infarction. Results We found 18 patients with splenic infarction. The average age was 78 years, and about half of patients had abdominal pain; however, the other half did not have abdominal pain. One-third of patients with splenic infarction died. Leukocytosis with neutrophilia, a decrease of lymphocytes, anemia, hypoalbuminemia, and liver dysfunction were observed. Fibrinogen was decreased and D-dimer was remarkably elevated. Lactate dehydrogenase (LDH) and C-reactive protein (CRP) were remarkably increased. Six patients (33.3%) had cancer, four patients (22.2%) had atrial fibrillation, and four patients (22.2%) had infection. We found 466 case reports on splenic infarction published from 1975 to 2021. Recently, the number of case reports on splenic infarction due to infection, especially, coronavirus disease 2019 (COVID-19), has been remarkably increasing. Furthermore, we found that leukocytosis, a decrease of lymphocytes, elongated activated partial thromboplastin time, decrease of fibrinogen, liver dysfunction, elevation of LDH and blood urea nitrogen can be the prognosis predicting factors for patients with splenic infarction. Conclusion Our study elucidated clinical, hematological, biochemical and radiological characteristics for patients with splenic infarction. We newly found significant differences in blood cell counts, coagulation markers, transaminases, LDH and blood urea nitrogen between patients who died and those who survived, suggesting that these parameters can be the prognosis predicting factors for splenic infarction. Further, our systematic review on case reports about splenic infarction showed the etiology of splenic infarction and the trend of the causative diseases.

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“…У детей ИС встречается в основном на фоне инфекционных заболеваний, в частности, микоплазменной пневмо нии, малярии [15]. Также относительно часто ИС у детей описан при гематоло гических заболеваниях, в частности, при серповидноклеточной анемии.…”

Section: особенности инфаркта селезенки у детей и подростковunclassified

Massive Splenic Infarction in a Child. Literature Review and Comparative Observations

Olkhova

Sholokhova

Mukaseeva

et al. 2022

jour

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Massive splenic infarction (SI) is an extremely rare disease in childhood, the genesis of which is not always clear. Most often in children, SI develops against the background of oncohematological (in particular, myeloid leukemia), hematological (sickle cell anemia) and infectious (malaria, mononucleosis, cytomegalovirus infection) diseases and is small in size. Two own observations are presented, unique in the absence of a clear cause of SI and the massiveness of the lesion. In the first case, a 10yearold girl was admitted to the hospital on about the 10th day of illness with complaints of undefined abdominal pain, about which she had already twice applied to other hospitals in Moscow. SI was suspected on ultrasound and confirmed on CT, and then the echographic dynamics of SI was followed for more than 2 months. Against the background of anticoagulant, antibacterial and symptomatic therapy, recovery was achieved. In the second case, total SI was observed in a premature infant with severe multiple organ failure. The publication is extensively illustrated and contains a brief review of the literature.

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Multiple Splenic Infarcts Complicating Plasmodium vivax Malaria

Cited by 4 publications

References 11 publications

Ultrasonic Diagnostics of Spleen Infarction in a Hematological Patient

Ultrasonic Diagnostics of Spleen Infarction in a Hematological Patient

Clinical, Hematological, Biochemical and Radiological Characteristics for Patients With Splenic Infarction: Case Series With Literature Review

Massive Splenic Infarction in a Child. Literature Review and Comparative Observations

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