Multiple sclerosis: correlation of psychiatric admissions to onset of initial symptoms

Abstract

ABSTRACT— Forty‐two (12%) of a total of 366 patients with multiple sclerosis (MS) had psychiatric admissions. Of these, 34 (81%) had their first psychiatric admission in conjunction with or after the onset of MS. Classification by psychiatric diagnosis showed that there was a significant positive correlation between the onset of MS and the first psychiatric admission for psychoses and transient situational disorders, but not for neuroses.

Psychiatric Symptoms Accompanying Multiple Sclerosis Onset: A Case Report

“…5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports. 5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports.…”

Psychiatric Symptoms Accompanying Multiple Sclerosis Onset: A Case Report

“…5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports. 5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports.…”

Functional neurological disorder and multiple sclerosis: a systematic review of misdiagnosis and clinical overlap

“…Although widely acknowledged, there is scant data on the prevalence of FND comorbidity with MS [ 45 , 46 ]. In a study of 366 patients with MS in Denmark in the 1970s and 80s, five (1%) had psychiatric admissions for “hysteric” neuroses in relation to and after the onset of MS [ 47 ]. A case series of four similar patients with both MS and “hysteria” was published in JAMA in 1980 [ 48 ].…”

The borderland of multiple sclerosis and functional neurological disorder: A call for clinical research and vigilance

“…Similarly, cases of coexisting MS and FND have been reported [39][40][41]. An older (1988) case series on 366 MS patients reported 1% of hysteric neuroses [42] and a more recent (2011) study found that 13% of patients with MS (32/252) had a symptom "somewhat or not at all explained by MS", suggesting coexisting FND [43].…”

Psychiatric Symptoms Accompanying Multiple Sclerosis Onset: A Case Report

“…5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports. 5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports.…”

Functional neurological disorder and multiple sclerosis: a systematic review of misdiagnosis and clinical overlap

“…Although widely acknowledged, there is scant data on the prevalence of FND comorbidity with MS [ 45 , 46 ]. In a study of 366 patients with MS in Denmark in the 1970s and 80s, five (1%) had psychiatric admissions for “hysteric” neuroses in relation to and after the onset of MS [ 47 ]. A case series of four similar patients with both MS and “hysteria” was published in JAMA in 1980 [ 48 ].…”

The borderland of multiple sclerosis and functional neurological disorder: A call for clinical research and vigilance

“…Similarly, cases of coexisting MS and FND have been reported [39][40][41]. An older (1988) case series on 366 MS patients reported 1% of hysteric neuroses [42] and a more recent (2011) study found that 13% of patients with MS (32/252) had a symptom "somewhat or not at all explained by MS", suggesting coexisting FND [43].…”

Psychiatric Symptoms Accompanying Multiple Sclerosis Onset: A Case Report

“…5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports. 5,7 As for MS, in particular, psychotic symptoms have rarely been found among initial manifestions of the disease, as illustrated in retrospective studies 6,[8][9][10][11] and case reports.…”

Functional neurological disorder and multiple sclerosis: a systematic review of misdiagnosis and clinical overlap

“…Although widely acknowledged, there is scant data on the prevalence of FND comorbidity with MS [ 45 , 46 ]. In a study of 366 patients with MS in Denmark in the 1970s and 80s, five (1%) had psychiatric admissions for “hysteric” neuroses in relation to and after the onset of MS [ 47 ]. A case series of four similar patients with both MS and “hysteria” was published in JAMA in 1980 [ 48 ].…”

The borderland of multiple sclerosis and functional neurological disorder: A call for clinical research and vigilance

“…Similarly, cases of coexisting MS and FND have been reported [39][40][41]. An older (1988) case series on 366 MS patients reported 1% of hysteric neuroses [42] and a more recent (2011) study found that 13% of patients with MS (32/252) had a symptom "somewhat or not at all explained by MS", suggesting coexisting FND [43].…”