2020
DOI: 10.1590/s1984-29612020086 View full text |Buy / Rent full text
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Abstract: Semi-intensive equine breeding system favors gastrointestinal nematode infections. The treatment of these infections is based on the use of anthelmintics. However, the inappropriate use of these drugs has led to parasitic resistance to the available active principles. The objective of this study was to evaluate the efficacy of the main classes of antiparasitic (ATP) used in control in adult and young animals, including: benzimidazoles (fenbendazole), pyrimidines (pyrantel pamoate), macrocyclic lactones (iverme… Show more

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“…It is remarkable that Table 1 contains six Brazilian studies reporting macrocyclic lactone resistance, which is almost half of all studies reporting resistance to this anthelmintic class. Several of these studies documented clearly reduced macrocyclic lactone efficacy in several groups and to several members of this class ( Toscan et al, 2012 ; Flores et al, 2020 ; Martins et al, 2021 ; Lignon et al, 2021 ), and one of them was a terminal study with intestinal worm counts confirming resistance to ivermectin in two cohorts ( Felippelli et al, 2015 ), providing strong evidence for these findings. In 2020, we documented the first case of macrocyclic lactone resistance in equine strongylids in the US ( Nielsen et al, 2020 ).…”
Section: Cyathostominsmentioning
“…Thus, X means that resistance was tested, but not found, and X-AR means that resistance was tested and found. Country Publication Benzimidazoles Pyrimidines Macrocyclic lactones Algeria Boulkaboul et al (2006) X-AR X Australia Pook et al (2002) X-AR X-AR X Abbas et al (2021) X-AR X-AR Belgium Dorny et al (2000) X-AR X-AR Brazil Toscan et al (2012) X-AR Canever et al (2013) X-AR X-AR X-AR Felippelli et al (2015) X-AR Saes et al (2016) X-AR X Vera et al (2020) X-AR X Flores et al (2020) X-AR X-AR X-AR Martins et al (2021) X-AR X-AR Lignon et al (2021) <...…”
Section: Cyathostominsmentioning