1982
DOI: 10.1001/archderm.118.2.136
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Multiple hamartoma syndrome with endometrial carcinoma and the sign of Leser-Trelat

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Cited by 7 publications
(4 citation statements)
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“…Abnormalities of the female reproductive tract are common and have been reported in 55% of patients (7). Abnormalities include benign ovarian cyst, teratoma, uterine leiomyoma, endometrial adenocarcinoma and carcinoma of the uterine cervix (7,57,64,66–68). Functional abnormalities particularly menstrual irregularities have been described (7).…”
Section: Clinical Presentationmentioning
confidence: 99%
“…Abnormalities of the female reproductive tract are common and have been reported in 55% of patients (7). Abnormalities include benign ovarian cyst, teratoma, uterine leiomyoma, endometrial adenocarcinoma and carcinoma of the uterine cervix (7,57,64,66–68). Functional abnormalities particularly menstrual irregularities have been described (7).…”
Section: Clinical Presentationmentioning
confidence: 99%
“…La gran mayoría de los artículos hallados corresponden al informe de uno o pocos pacientes con queratosis seborreica eruptiva y alguna neoplasia, generalmente gastrointestinal y pancreatobiliar , aunque hay casos de la lesión cutánea asociada a linfoma de células T, linfoma no Hodgkin, leucemia mieloide o linfoide crónica, melanoma; cáncer en pulmón, útero, mama, ovario, próstata, riñón, vejiga, nasofaringe, médula espinal, tiroides y hueso (3,(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46). Aunque menos, también hay publicaciones de pacientes con la lesión dermatológica y condiciones como hiperinsulinismo, eritrodermia, trasplante cardiaco, tratamiento con citarabina o adalimmumab, VIH, adenoma de células Figura 1.…”
Section: Resultsunclassified
“… 5 have postulated that hormonal factors (epidermal growth factor and transforming growth factor (TGF)‐α) that cause seborrheic keratosis with a hyperplastic effect lead to acanthosis nigricans by affecting the flexor surfaces, causing hyperpigmentation and papillomatosis. Acquired ichtyosis, 6 Cowden's disease, 7 acrokeratosis paraneoplastica, 8 hypertricosis lanuginosa, 9 fluorid cutaneous papillomatosis 10 and tilosis 11 can also be observed with Leser‐Trelat sign.…”
Section: Discussionmentioning
confidence: 99%