“…As stated, it may be absent and this, at one time regarded as a rare phenomenon, is well demonstrated in those cases of multiple tumours in which only some show pain or tenderness. In one case with 48 tumours, none was painful (Weidman and Wise, 1937); of 12 tumours, one was painful (Slepyan, 1944) ; of 90 tumours, 2 were painful (Eyster and Montgomery, 1950) and in the present series, in one case which showed 26 tumours only one was painful. The minor degrees are in the form of localized discomfort, perhaps on pressure, mild tinglings or merely localized "sensitiveness" in the area.…”