Multiple extractions in a patient with factor VII deficiency

Hémostase locale en Chirurgie orale. 2èmepartie : efficacité de la colle de fibrine

“…C'est sans doute l'une des plus anciennes. Cette technique consiste à mettre en place après l'intervention des gouttières afin d'exercer une pression sur la plaie pendant quelques jours [2,[5][6][7]. Ces gouttières ont l'avantage de protéger le caillot, mais malheureusement leur efficacité reste limitée car il persiste souvent une suffusion hémorragique.…”

Hémostase locale en Chirurgie orale. 2èmepartie : efficacité de la colle de fibrine

“…C'est sans doute l'une des plus anciennes. Cette technique consiste à mettre en place après l'intervention des gouttières afin d'exercer une pression sur la plaie pendant quelques jours [2,[5][6][7]. Ces gouttières ont l'avantage de protéger le caillot, mais malheureusement leur efficacité reste limitée car il persiste souvent une suffusion hémorragique.…”

Factor Vii Deficiency

“…Intermediate purity factor IX concentrates (prothrombin complex concentrates), i.e. concentrates that are not produced by either monoclonal or recombinant techniques, contain variable amounts of factor VII and have been successfully used to manage patients with factor VII deficiency (White et al , 1979; Sumi et al , 1985). The amount of factor VII in each of these concentrates is very variable but is usually indicated by the manufacturer and this can then be used to calculate the amount required for replacement therapy.…”

“…Although this seems illogical when one considers the short half‐life of factor VII, in practice it seems successful (Cohen et al , 1995). For surgery, doses ranging from 8 to 40 U/kg every 4–6 h have been successfully used (Schricker & Neidhardt, 1981; Greene & McMillan, 1982; Gagliardi et al , 1983; Sumi et al , 1985; Ferster et al , 1993). Careful monitoring of patients receiving FVII concentrates is essential to prevent excessively high peaks and troughs.…”

“…A number of plasma‐derived factor VII concentrates have been developed and have been successfully used to manage patients with inherited factor VII deficiency with spontaneous bleeding episodes or undergoing a wide variety of surgical procedures (Mariani et al , 1978; Dike et al , 1980; Gagliardi et al , 1983; Sumi et al , 1985; Eikenboom et al , 1992; Robertson et al , 1992; Rivard et al , 1994). Factor VII concentrates have also been successfully used for prophylaxis against bleeds in children with severe factor VII deficiency and suggested guidelines for the administration of factor VII for long‐term prophylaxis are in the range of 10–50 U/kg one to three times a week.…”

The rare coagulation disorders – review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation

“…Recent work using the thrombin generation test (TGT) has suggested that levels of 2 U dL )1 are sufficient to normalize the TGT although this has not been used to monitor replacement therapy [105]. Factor VII concentrate -For surgery, doses of FVII concentrate ranging from 8 to 40 U kg )1 every 4-6 h have been successfully used [89,[106][107][108][109]. Careful monitoring of patients receiving FVII concentrates is essential to prevent excessively high peaks and troughs.…”

Hémostase locale en Chirurgie orale. 2èmepartie : efficacité de la colle de fibrine

“…C'est sans doute l'une des plus anciennes. Cette technique consiste à mettre en place après l'intervention des gouttières afin d'exercer une pression sur la plaie pendant quelques jours [2,[5][6][7]. Ces gouttières ont l'avantage de protéger le caillot, mais malheureusement leur efficacité reste limitée car il persiste souvent une suffusion hémorragique.…”

Factor Vii Deficiency

“…Intermediate purity factor IX concentrates (prothrombin complex concentrates), i.e. concentrates that are not produced by either monoclonal or recombinant techniques, contain variable amounts of factor VII and have been successfully used to manage patients with factor VII deficiency (White et al , 1979; Sumi et al , 1985). The amount of factor VII in each of these concentrates is very variable but is usually indicated by the manufacturer and this can then be used to calculate the amount required for replacement therapy.…”

“…Although this seems illogical when one considers the short half‐life of factor VII, in practice it seems successful (Cohen et al , 1995). For surgery, doses ranging from 8 to 40 U/kg every 4–6 h have been successfully used (Schricker & Neidhardt, 1981; Greene & McMillan, 1982; Gagliardi et al , 1983; Sumi et al , 1985; Ferster et al , 1993). Careful monitoring of patients receiving FVII concentrates is essential to prevent excessively high peaks and troughs.…”

“…A number of plasma‐derived factor VII concentrates have been developed and have been successfully used to manage patients with inherited factor VII deficiency with spontaneous bleeding episodes or undergoing a wide variety of surgical procedures (Mariani et al , 1978; Dike et al , 1980; Gagliardi et al , 1983; Sumi et al , 1985; Eikenboom et al , 1992; Robertson et al , 1992; Rivard et al , 1994). Factor VII concentrates have also been successfully used for prophylaxis against bleeds in children with severe factor VII deficiency and suggested guidelines for the administration of factor VII for long‐term prophylaxis are in the range of 10–50 U/kg one to three times a week.…”

The rare coagulation disorders – review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation

“…Recent work using the thrombin generation test (TGT) has suggested that levels of 2 U dL )1 are sufficient to normalize the TGT although this has not been used to monitor replacement therapy [105]. Factor VII concentrate -For surgery, doses of FVII concentrate ranging from 8 to 40 U kg )1 every 4-6 h have been successfully used [89,[106][107][108][109]. Careful monitoring of patients receiving FVII concentrates is essential to prevent excessively high peaks and troughs.…”

Hémostase locale en Chirurgie orale. 2èmepartie : efficacité de la colle de fibrine

“…C'est sans doute l'une des plus anciennes. Cette technique consiste à mettre en place après l'intervention des gouttières afin d'exercer une pression sur la plaie pendant quelques jours [2,[5][6][7]. Ces gouttières ont l'avantage de protéger le caillot, mais malheureusement leur efficacité reste limitée car il persiste souvent une suffusion hémorragique.…”

Factor Vii Deficiency

“…Intermediate purity factor IX concentrates (prothrombin complex concentrates), i.e. concentrates that are not produced by either monoclonal or recombinant techniques, contain variable amounts of factor VII and have been successfully used to manage patients with factor VII deficiency (White et al , 1979; Sumi et al , 1985). The amount of factor VII in each of these concentrates is very variable but is usually indicated by the manufacturer and this can then be used to calculate the amount required for replacement therapy.…”

“…Although this seems illogical when one considers the short half‐life of factor VII, in practice it seems successful (Cohen et al , 1995). For surgery, doses ranging from 8 to 40 U/kg every 4–6 h have been successfully used (Schricker & Neidhardt, 1981; Greene & McMillan, 1982; Gagliardi et al , 1983; Sumi et al , 1985; Ferster et al , 1993). Careful monitoring of patients receiving FVII concentrates is essential to prevent excessively high peaks and troughs.…”

“…A number of plasma‐derived factor VII concentrates have been developed and have been successfully used to manage patients with inherited factor VII deficiency with spontaneous bleeding episodes or undergoing a wide variety of surgical procedures (Mariani et al , 1978; Dike et al , 1980; Gagliardi et al , 1983; Sumi et al , 1985; Eikenboom et al , 1992; Robertson et al , 1992; Rivard et al , 1994). Factor VII concentrates have also been successfully used for prophylaxis against bleeds in children with severe factor VII deficiency and suggested guidelines for the administration of factor VII for long‐term prophylaxis are in the range of 10–50 U/kg one to three times a week.…”

The rare coagulation disorders – review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation

“…Recent work using the thrombin generation test (TGT) has suggested that levels of 2 U dL )1 are sufficient to normalize the TGT although this has not been used to monitor replacement therapy [105]. Factor VII concentrate -For surgery, doses of FVII concentrate ranging from 8 to 40 U kg )1 every 4-6 h have been successfully used [89,[106][107][108][109]. Careful monitoring of patients receiving FVII concentrates is essential to prevent excessively high peaks and troughs.…”