volume 30, issue 2, P423-437 2012
DOI: 10.3233/jad-2012-111304
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Pei-Ning Wang, Kun-Hsien Chou, Jiing-Feng Lirng, Ker-Neng Lin, Wei-Ta Chen, Ching-Po Lin

Abstract: Different diffusivity measurements in diffusion-tensor imaging (DTI) could be helpful for detecting the distinct mechanisms of white matter degeneration in Alzheimer's disease (AD). However, few studies have explored the changes of white matter in amnestic mild cognitive impairment (aMCI) and AD by whole-brain voxel-wise analyses of all diffusivity indices. The association between grey matter atrophy and white matter damage measured by distinct diffusivities is still uncertain. Structural magnetic resonance im…

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