Archives of Dermatology
 1980
DOI: 10.1001/archderm.116.4.433
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Multiple clear cell acanthomas

H. Trau1

Abstract: Clear cell acanthoma is usually a solitary benign epidermal tumor. Multiple lesions are rarely encountered, and only 11 such cases could be found in the literature. In all cases, the lesions were limited to the lower extremities. A few of the patients have had ichthyosis and/or varicose veins. We describe a 12th patient who, in addition to leg lesions, had lesions on the trunk and associated dry skin.

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“…The tumor is usually asymptomatic and solitary, but occasionally patients present multiple lesions. 2 There may be a peripheral epidermal collarette or superimposed serous exudate. Clear cell acanthoma does not show an ethnic or gender predilection and shows a peak incidence between 50 and 60 years of age.…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The tumor is usually asymptomatic and solitary, but occasionally patients present multiple lesions. 2 There may be a peripheral epidermal collarette or superimposed serous exudate. Clear cell acanthoma does not show an ethnic or gender predilection and shows a peak incidence between 50 and 60 years of age.…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…[1] Trau, et al . [2] summarized 12 cases of CCA with multiple lesions and showed that all the multiple lesions were located on the lower limbs. Our patient is the first case of multiple facial CCAs with a giant lesion.…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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