2016
DOI: 10.1016/j.joen.2016.01.022
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Abstract: These results suggested that AP affected blood homeostasis by altering the serum levels of inflammatory cytokines and NO.

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Cited by 57 publications
(79 citation statements)
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“…Furthermore, in pregnant women AP seems to associate with shorter pregnancy duration and with intrauterine growth restriction [36]. The impact of AP systemically can be by the alteration of serum levels of different cytokines and nitric oxide, as has been shown in rat models [37]. Hence endodontic infections need indeed be considered simultaneously with other dental infections under the paradigm of oral infections and general health.…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, in pregnant women AP seems to associate with shorter pregnancy duration and with intrauterine growth restriction [36]. The impact of AP systemically can be by the alteration of serum levels of different cytokines and nitric oxide, as has been shown in rat models [37]. Hence endodontic infections need indeed be considered simultaneously with other dental infections under the paradigm of oral infections and general health.…”
Section: Discussionmentioning
confidence: 99%
“…Because immunolabelling of both the cells and the extracellular matrix is of great importance, semiquantitative analysis, which provides information on the numbers of immunolabelling cells and immunolabelling intensity of the extracellular matrix, was performed (Cintra et al . ). The scores were assigned as follows (adapted from Cintra et al .…”
Section: Methodsmentioning
confidence: 97%
“…The scores were assigned as follows (adapted from Cintra et al . ): 0, immunolabelling missing; 1, low standard of immunolabelling; 2, moderate standard of immunolabelling; 3, severe standard of immunolabelling; and 4, very severe standard of immunolabelling.…”
Section: Methodsmentioning
confidence: 99%
“…The influence of Lactobacillus rhamnosus and Lactobacillus acidophilus lowered the severity of inflammatory infiltrate and proinflammatory cytokine expression (IL-1b and IL6) concomitantly with higher anti-inflammatory cytokine expression (IL-10). The 30-day experimental period was chosen because it is considered long enough for chronic AP development (Gomes-Filho et al 2015, Cintra et al 2016, Dal-Fabbro et al 2019). Therefore, the null hypothesis was rejected.…”
Section: Discussionmentioning
confidence: 99%
“…The coronal pulp tissue was exposed and kept open to the oral cavity until euthanasia (Cintra et al 2016, Dal-Fabbro et al 2019). Coronal pulp tissue was exposed and disorganized through an access cavity in the crown of the left and right maxillary first molars using a spherical carbide bur with 0.5 mm diameter (Jet Carbide ¼, Kavo Kerr Group, Orange, CA, USA) used under a surgical microscope (Decius, DF Vasconcelos, Rio de Janeiro, Brazil).…”
Section: Induction Of Apmentioning
confidence: 99%