Multiple agminate spindle and epithelioid cell nevi in an adult

Weimar, V. M.

doi:10.1001/archderm.114.9.1383b

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1987

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Cited by 7 publications

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“…Twenty-seven cases of agminated type have been reported, all but three [8][9][10] occurring in children, usually involving the face, trunk or arms. The lesions arise both on congenital hyperpigmented maculae and on grossly appearing normal skin, as in our case.…”

Section: Commentmentioning

confidence: 99%

Multiple agminated Spitz nevi of the penis

Monfrecola

Ianniello

Donofrio

et al. 1994

Acad Dermatol Venereol

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Section: Commentmentioning

confidence: 99%

Multiple agminated Spitz nevi of the penis

Monfrecola

Ianniello

Donofrio

et al. 1994

Acad Dermatol Venereol

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Multiple agminate Spitz naevi: Review of the literature and report of a case with distinctive immunohistological features

1987

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We describe a 13-year-old girl with multiple pigmented nodules and plaques arranged in a cluster in the right lumbar region, which had developed since infancy. Eleven of 15 lesions which were examined histologically were found to be Spitz naevi. The remaining four lesions were compound naevocellular naevi, and two of them showed focal dysplasia. Eight Spitz naevi were investigated immunohistologically with monoclonal antibodies against HLA-antigens and malignancy-associated melanocytic antigens which are rarely present in common naevi. Naevus cells in all lesions expressed HLA-ABC antigens, but lacked HLA-DR antigens in seven of the eight lesions. All naevi were positive for 'constitutive' (KG-6-56) and 'early' (K-1-2) markers of naevomelanocytic cells. In five of the eight Spitz naevi, at least one of the three malignancy-associated melanocytic antigens PAL-M1, A-1-43 and A-10-33 was found. The expression of malignancy-associated antigens in multiple agminate Spitz naevi is at variance with their benign clinical course.

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Agminate Spitz naevi arising on hyperpigmented patches

et al. 1994

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In 1948 Dr Sophie Spitz described criteria that distinguished juvenile melanoma from malignant melanoma. Since then the cases of eruptive Spitz naevi have been reported arising on normal skin, on lightly pigmented patches and on hypopigmented patches. There are only 12 reports of Spitz naevi arising on hyperpigmented patches: we describe here three further cases, all on the arms of children, seen in our department in a single year.

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Multiple agminate spindle and epithelioid cell nevi in an adult

Cited by 7 publications

References 0 publications

Multiple agminated Spitz nevi of the penis

Multiple agminated Spitz nevi of the penis

Multiple agminate Spitz naevi: Review of the literature and report of a case with distinctive immunohistological features

Agminate Spitz naevi arising on hyperpigmented patches

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