Multinational development of a questionnaire assessing patient satisfaction with anticoagulant treatment: the 'Perception of Anticoagulant Treatment Questionnaire' (PACT-Q©)

Prins, Martin H.; Marrel, Alexia; Carita, Paulo; Anderson, David R.; Bousser, Marie‐Germaine; Crijns, Harry J.G.M.; Consoli, Silla M.; Arnould, B

doi:10.1186/1477-7525-7-9

Cited by 49 publications

(69 citation statements)

References 36 publications

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“…The clinical applications of OACs have been evidenced through studies of various conditions, such as atrial fibrillation, venous thromboembolism, patients with prosthetic heart valves, congestive heart failure, myocardial infarction and other special situations (1) . The therapeutic action of the OAC can be influenced by numerous conditions that alter its absorption and metabolism.…”

Section: Introductionmentioning

confidence: 99%

“…The intake of foods rich in fats and vitamin K, drugs containing acetylsalicylic acid and alcohol can be cited as examples. The changes in the desired levels of blood anticoagulation can cause hemorrhagic or thromboembolic events, harming the patient (1) . For the evaluation of the anticoagulation levels, laboratory control is accomplished through frequent blood sampling in order to obtain the International Normalized Ratio (INR) (2) www.eerp.usp.br/rlae Corbi ISA, Dantas RAS, Pelegrino FM, Carvalho ARS.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, the success of each therapy depends on how each individual perceives its benefits (5) . Positive perceptions are related to a better control of the oral anticoagulation therapy and better HRQoL (6) , with the reduction of the number of oral anticoagulation therapy complications associated with improved HRQoL (1) .…”

Section: Introductionmentioning

confidence: 99%

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Health related quality of life of patients undergoing oral anticoagulation therapy

Corbi¹,

Dantas

Pelegrino³

et al. 2011

Rev. Latino-Am. Enfermagem

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This is a descriptive cross-sectional study, which aimed to analyze the health related quality of life (HRQoL) and its relationship with gender, age, duration and indication for the use of oral anticoagulants. A total of 178 patients were interviewed and the HRQoL was assessed through eight domains of the SF-36. The descriptive statistics used were, the Student's t, ANOVA and Tukey's tests for the comparison of the means between the groups. The indication for use was predominantly the metallic prosthetic heart valve (50%) with warfarin the most widely prescribed anticoagulant (83.3%). Calidad de vida relacionada a la salud de pacientes que usan anticoagulación oralSe trata de un estudio descriptivo, de tipo corte transversal, que tuvo como objetivo analizar la calidad de vida relacionada a la salud (CVRS) y su relación con sexo, edad, tiempo e indicación de uso de anticoagulantes orales. Fueron entrevistados 178 pacientes y la CVRS fue evaluada por los ocho dominios del SF-36. Fue utilizada estadística descriptiva, las pruebas: t Student, ANOVA y Tukey, para comparación de los promedios entre los grupos. La indicación para el uso fue predominantemente la prótesis cardíaca metálica (50%) y la warfarina el anticoagulante más prescrito (83,3%).Los promedios de los dominios del SF-36 variaron de 82 (Aspectos sociales) a 54,8 (Aspectos físicos). Mujeres, ancianos, y pacientes con diagnóstico de fibrilación atrial y con menos de un año de uso del medicamento, presentaron peor evaluación de la CVRS.Los resultados obtenidos pueden orientar acciones de enfermería, en la medida en que indican posibles asociaciones entre la CVRS y las variables sociodemográficas y clínicas de los pacientes.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Health related quality of life of patients undergoing oral anticoagulation therapy

Corbi¹,

Dantas

Pelegrino³

et al. 2011

Rev. Latino-Am. Enfermagem

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“…Tais fatores podem estar relacionados às variações na ingestão de alimentos contendo vitamina K, dieta rica em gorduras, consumo de álcool, interação medicamentosa, doenças hepáticas, doenças virais, hipotireoidismo e fatores genéticos (LANSBERG et al, 2012;PRINS et al, 2009). …”

Section: Apresentação E Relevância Do Temaunclassified

“…Todos os fatores associados à terapia podem influenciar a qualidade vida dos indivíduos de forma positiva ou negativa (LANCASTER et al, 1991;PRINS et al, 2009 A avaliação da QVRS de pacientes que fazem uso de ACOs se faz necessária, uma vez que o tratamento pode ser influenciado pelas mudanças de hábitos e comportamentos, e pode ocasionar eventos adversos que acarretam um impacto negativo na vida do paciente e a sua não adesão ao tratamento. As dimensões de qualidade de vida que têm sido investigadas referem-se à satisfação geral com tratamento da anticoagulação oral, autoeficácia, rede de apoio social, desagrados diários e angústia (GADISSEUR et al, 2004;GONZÁLEZ et al, 2004;SAWICKI, 1999) e também a limitação, tarefa/sobrecarga e impacto psicológico (positivo e negativo) da terapêutica (SAMSA et al, 2004).…”

Section: Apresentação E Relevância Do Temaunclassified

Efeitos de um programa educativo na qualidade de vida relacionada à saúde e na adesão à terapia de anticoagulação oral: estudo clínico randomizado

Corbi¹

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DEDICATÓRIAExperimental study with random distribution in two groups (Intervention or Control), which assessed the health-related quality of life and medication treatment adherence of patients who were hospitalized to adjust the oral anticoagulation drug dosage, according to their participation in an educational group (Intervention Group -IG) or in routine care (Control Group -CG). The groups were also compared according to their general self-efficacy and presence of anxiety and depression symptoms at two times: upon hospitalization (T 1 ) and two months after discharge from hospital (T 2 ). The study was developed at a public hospital in the interior of São Paulo State, Brazil, from March 2011 till December 2012. In total, 113 patients were considered eligible for the study, randomized between CG (N=58) and IG (N=55). The randomization took place after the patients' stratification into low, medium and high bleeding risk, according to The Outpatient Bleeding Risk Index. The patients who participated in the educative program received individualized orientations, using illustrative material, during the hospitalization. After discharge, the orientations were provided through telephone contact during the first and fourth week. To assess the research variables, the versions of the Duke Anticoagulation Satisfaction Scale, Treatment Adherence Measures, Hospital Anxiety and Depression Scale and General Perceived Self-Efficacy Scale validated for Brazilian Portuguese were used. After two months of monitoring, 44 participants completed the followup in CG (75.8% of participants at T 1 ) and 38 in IG (69.1%). The data were assessed by means of descriptive statistics and comparison of means for the variables of interest between the groups (independent Student's t) and intra-groups (paired Student's t-test), upon the hospitalization and two months after discharge. The significance level adopted was 0.05. When comparing the patient groups that completed the follow-up or not, we found similarities in sociodemographic and clinical variables and related to the oral anticoagulation therapy. These similarities were also observed when comparing the control and intervention groups during the hospitalization. As regards the health-related quality of life, treatment adherence, anxiety and depression symptoms and self-efficacy, the results reveal similarities between CG and IG at T 1 and T 2 , not confirming our study hypotheses for T 2 . At T 2 , the differences in the HRQoL (p=0.65), adherence (p=0.89), anxiety (p=0.20), depression (p=0.27) and selfefficacy (p=0.65) scores could not be confirmed when considering the participation in the educative program. In view of the results obtained in the present study, we conclude that, for patients with previous experience in oral anticoagulation treatment, the educative strategy used was not efficient to improve the selected response variables. From the clinical viewpoint, this result is relevant for the health professionals who deliver care to this population of oral anticoagulation drug user...

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Factors influencing patient’s perception of long-term treatment with low-molecular-weight heparins for cancer-associated thrombosis: an updated analysis of TROPIQUE, a prospective observational study

Debourdeau

Arvers

Hij

et al. 2019

Support Care Cancer

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Multinational development of a questionnaire assessing patient satisfaction with anticoagulant treatment: the 'Perception of Anticoagulant Treatment Questionnaire' (PACT-Q©)

Abstract: Background: The side effects and burden of anticoagulant treatments may contribute to poor compliance and consequently to treatment failure. A specific questionnaire is necessary to assess patients' needs and their perceptions of anticoagulant treatment.

Cited by 49 publications

References 36 publications

Health related quality of life of patients undergoing oral anticoagulation therapy

Health related quality of life of patients undergoing oral anticoagulation therapy

Efeitos de um programa educativo na qualidade de vida relacionada à saúde e na adesão à terapia de anticoagulação oral: estudo clínico randomizado

Factors influencing patient’s perception of long-term treatment with low-molecular-weight heparins for cancer-associated thrombosis: an updated analysis of TROPIQUE, a prospective observational study

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