Multimicronutrient Supplementation for Undernourished Pregnant Women and the Birth Size of Their Offspring

Abstract

Compared with iron and folic acid supplementation, the administration of multimicronutrients to undernourished pregnant women may reduce the incidence of low birth weight and early neonatal morbidity.

Circulating angiogenic factors and their association with birth outcomes in preeclampsia

“…49 It is also known that babies born to preeclamptic mothers will be at increased risk for various metabolic syndromes, such as cardiovascular disease, later in life. 50 In this study, cord plasma PlGF levels were below the detection limit in both groups, and similar findings were previously reported. 51,15 In our study, sFlt-1 levels in cord plasma were increased, although they were not significant in preeclampsia, consistent with earlier reports.…”

Circulating angiogenic factors and their association with birth outcomes in preeclampsia

“…49 It is also known that babies born to preeclamptic mothers will be at increased risk for various metabolic syndromes, such as cardiovascular disease, later in life. 50 In this study, cord plasma PlGF levels were below the detection limit in both groups, and similar findings were previously reported. 51,15 In our study, sFlt-1 levels in cord plasma were increased, although they were not significant in preeclampsia, consistent with earlier reports.…”

Multiple Micronutrient Supplementation during Pregnancy in Low-Income Countries: A Meta-Analysis of Effects on Birth Size and Length of Gestation

“…The increase in birthweight and reduction in LBW and SGA births was consistent with the results of an earlier meta-analysis [9] and with other, more recent trials [29, 30]. There was no increase in other birth measurements.…”

An Effectiveness Trial of Multiple Micronutrient Supplementation during Pregnancy in Vietnam: Impact on Birthweight and on Stunting in Children at around 2 Years of Age

“…The LBW rates in the districts where mothers were taking multiple micronutrients were half that in the district where mothers were taking ironfolic acid tablets. The mean birthweights of around 3 kg found in the three districts of the Red River Delta are similar to those reported in studies from Indonesia [19], Zimbabwe [18], and Niger [16], as compared with less than 3 kg in supplementation trials in Nepal [17] and India [22]. The differences in mean birthweight of 100 g (Binh Luc) and 150 g (Kim Son) in the districts receiving multiple micronutrients compared with the district receiving iron-folic acid are twice as large as those found in these other trials of multiple micronutrient supplementation during pregnancy and are similar to those achieved by giving mothers food supplements during pregnancy in the Gambia [23].…”

Circulating angiogenic factors and their association with birth outcomes in preeclampsia

“…49 It is also known that babies born to preeclamptic mothers will be at increased risk for various metabolic syndromes, such as cardiovascular disease, later in life. 50 In this study, cord plasma PlGF levels were below the detection limit in both groups, and similar findings were previously reported. 51,15 In our study, sFlt-1 levels in cord plasma were increased, although they were not significant in preeclampsia, consistent with earlier reports.…”

Multiple Micronutrient Supplementation during Pregnancy in Low-Income Countries: A Meta-Analysis of Effects on Birth Size and Length of Gestation

“…The increase in birthweight and reduction in LBW and SGA births was consistent with the results of an earlier meta-analysis [9] and with other, more recent trials [29, 30]. There was no increase in other birth measurements.…”

An Effectiveness Trial of Multiple Micronutrient Supplementation during Pregnancy in Vietnam: Impact on Birthweight and on Stunting in Children at around 2 Years of Age

“…The LBW rates in the districts where mothers were taking multiple micronutrients were half that in the district where mothers were taking ironfolic acid tablets. The mean birthweights of around 3 kg found in the three districts of the Red River Delta are similar to those reported in studies from Indonesia [19], Zimbabwe [18], and Niger [16], as compared with less than 3 kg in supplementation trials in Nepal [17] and India [22]. The differences in mean birthweight of 100 g (Binh Luc) and 150 g (Kim Son) in the districts receiving multiple micronutrients compared with the district receiving iron-folic acid are twice as large as those found in these other trials of multiple micronutrient supplementation during pregnancy and are similar to those achieved by giving mothers food supplements during pregnancy in the Gambia [23].…”

Circulating angiogenic factors and their association with birth outcomes in preeclampsia

“…49 It is also known that babies born to preeclamptic mothers will be at increased risk for various metabolic syndromes, such as cardiovascular disease, later in life. 50 In this study, cord plasma PlGF levels were below the detection limit in both groups, and similar findings were previously reported. 51,15 In our study, sFlt-1 levels in cord plasma were increased, although they were not significant in preeclampsia, consistent with earlier reports.…”

Multiple Micronutrient Supplementation during Pregnancy in Low-Income Countries: A Meta-Analysis of Effects on Birth Size and Length of Gestation

“…The increase in birthweight and reduction in LBW and SGA births was consistent with the results of an earlier meta-analysis [9] and with other, more recent trials [29, 30]. There was no increase in other birth measurements.…”

An Effectiveness Trial of Multiple Micronutrient Supplementation during Pregnancy in Vietnam: Impact on Birthweight and on Stunting in Children at around 2 Years of Age

“…The LBW rates in the districts where mothers were taking multiple micronutrients were half that in the district where mothers were taking ironfolic acid tablets. The mean birthweights of around 3 kg found in the three districts of the Red River Delta are similar to those reported in studies from Indonesia [19], Zimbabwe [18], and Niger [16], as compared with less than 3 kg in supplementation trials in Nepal [17] and India [22]. The differences in mean birthweight of 100 g (Binh Luc) and 150 g (Kim Son) in the districts receiving multiple micronutrients compared with the district receiving iron-folic acid are twice as large as those found in these other trials of multiple micronutrient supplementation during pregnancy and are similar to those achieved by giving mothers food supplements during pregnancy in the Gambia [23].…”