Multidrug-resistant bacteria isolated from patients hospitalized in Intensive Care Unit in University Hospital of Constantine, Algeria (2011 - 2015)

Abstract

ICU (26.3, 18.7, 14.3, 11.9 and 9.2% respectively). MRSA strains constituted over 65% of all S. aureus isolates and 30.3% of E. faecium were found to be vancomycin resistant. Extended spectrum β-lactmase producers were expressed in 53.2% and 50.6 from K. pneumoniae and E. coli. Carbapenem resistance among K. pneumoniae improved slightly from 2.89 to 4.21%. A. baumannii isolates exhibited extremely high levels of resistance to all antibiotics except colistin (100% sensitive). In addition, 80.4% of A. baumannii isolates were found to be resistant to imipenem. Imipenem resistant P. aeruginosa isolates showed 36.4%.

Extended-Spectrum β-Lactamase and Carbapenemase Producing Gram-Negative Bacilli Infections Among Patients in Intensive Care Units of Felegehiwot Referral Hospital: A Prospective Cross-Sectional Study

“…38 E. cloacae and P. aeruginosa isolates were the leading ESBL producers with K. pneumoniae and E. coli. This is consistent with findings reported in Indonesia, 39 Algeria 40 and India 37 where E. cloacae was the predominant ESBL producing isolate. In reports from Uganda, 6 Nepal, 30 Brazil 41 and Mexico, 28 E. coli and K. pneumoniae were also the most common ESBL producing isolates.…”

“…In spite of percentage differences, K. pneumoniae (4.21%) and P. aeruginosa (2.6%) were the predominant carbapenemase producing isolates in Algeria. 40 Similarly, K. pneumoniae (91%) and P. aeruginosa (66%) were the commonest carbapenemase producing organisms in Taiwan. 45 The burden of beta-lactamase producing bacterial infections among ICU patients is aggravated by the high percentage (81.5%) of multi-drug resistant strains.…”

“…The findings are comparable with a study from Algeria where P. aeruginosa and E. cloacae isolates were 100% resistant to sulfamethoxazoletrimethoprim, cefuroxime, cefotaxime, and ceftazidime. 40 In general, the reason for the observed resistance to different antibiotics among GNB isolates could be due to the syndromic management of patients and non-selective prescription of broad spectrum antibiotics to treat various sites of bacterial infections. In Ethiopia, syndromic management of patients and use of antibiotics without definite diagnosis and prescription are common practices which results in overuse and misuse of drugs that greatly contributes to the emergence and spreading of drug resistance.…”

Layer-By-Layer Self-Assembled Dip Coating for Antifouling Functionalized Finishing of Cotton Textile

“…The spread of pathogenic microbes through contaminated textiles is a major source of nosocomial infections [2]. Gram-negative and Gram-positive bacteria species such as Escherichia coli and Staphylococcus aureus are among those bacterial strains responsible for hospital-acquired infections [3][4][5]. In consideration of such concerns, the global demand for antifouling textiles has tremendously increased due to consumer awareness regarding hygiene, health, and safety [6].…”