Multi walled carbon nanotubes embedded conducting polymer based electrochemical aptasensor for estimation of malathion

Kaur, Navpreet; Thakur, Himkusha; Prabhakar, Nirmal

doi:10.1016/j.microc.2019.03.042

Cited by 42 publications

(8 citation statements)

References 30 publications

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“…Currently, water-soluble PThs are becoming increasingly applicable in chemo- and biosensing since their chain conformations and photophysical properties are sensitive to external stimuli including thermal or phototreatment, the change of solvent composition, and the introduction of chemical and biochemical targets Table presents a brief overview of different PThs and their derivatives based biosensors. ,− …”

Section: A Review Of Conjugated Polymer-based Aptasensors Since 2010:...mentioning

confidence: 99%

Conjugated Polymers for Aptasensing Applications

Salimian

Nardin

2023

Biomacromolecules

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Rapid and specific assaying of molecules that report on a pathophysiological condition, environmental pollution, or drug concentration is pivotal for establishing efficient and accurate diagnostic systems. One of the main components required for the construction of these systems is the recognition element (receptor) that can identify target analytes. Oligonucleotide switching structures, or aptamers, have been widely studied as selective receptors that can precisely identify targets in different analyzed matrices with minimal interference from other components in an antibody-like recognition process. These aptasensors, especially when integrated into sensing platforms, enable a multitude of sensors that can outperform antibody-based sensors in terms of flexibility of the sensing strategy and ease of deployment to areas with limited resources. Research into compounds that efficiently enhance signal transduction and provide a suitable platform for conjugating aptamers has gained huge momentum over the past decade. The multifaceted nature of conjugated polymers (CPs), notably their versatile electrical and optical properties, endows them with a broad range of potential applications in optical, electrical, and electrochemical signal transduction. Despite the substantial body of research demonstrating the enhanced performance of sensing devices using doped or nanostructure-embedded CPs, few reviews are available that specifically describe the use of conjugated polymers in aptasensing. The purpose of this review is to bridge this gap and provide a comprehensive description of a variety of CPs, from a historical viewpoint, underpinning their specific characteristics and demonstrating the advances in biosensors associated with the use of these conjugated polymers.

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Section: A Review Of Conjugated Polymer-based Aptasensors Since 2010:...mentioning

confidence: 99%

Conjugated Polymers for Aptasensing Applications

Salimian

Nardin

2023

Biomacromolecules

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“…In addition to optical sensors, electrochemical biosensors based on aptamer recognition can also achieve excellent pesticide detection. In 2019, an aptasensor was developed for malathion detection, consisting of polymer poly (3,4-ethylenedioxythiophene) (PEDOT) and carboxylated multi-walled carbon nanotubes (c-MWCNTs) ( Kaur et al, 2019 ). The aptamers were introduced onto the electrode surface via chemical bonds.…”

Section: Aptamer-based Recognition Of Pesticide Compoundsmentioning

confidence: 99%

Multiple Recognition-Based Sensor for Pesticide Residues

Chen

Zhu

et al. 2022

Front. Chem.

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The use of pesticides is gradually increasing to improve the yield and quality of crops. However, excessive pesticide use has led to a dramatic pollution increase in the environment and agricultural products, posing severe human health risks. Therefore, rapid, sensitive pesticide detection is essential. Various pesticides detection methods and products have been developed in recent years. This brief review summarized the point-of-care testing (POCT) detection of pesticides based on multiple recognition, including protein-, aptamer-, nanomaterial-, and macrocycle-based recognition. The review aimed to address the growing demands for regulating and destroying pesticides or other adverse agriculture-related applications in the real world.

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“…Moreover, in some cases concerning the determination of organophosphate pesticide, the concentrations determined are so small that it is hard to find the analytical problems corresponding to their value. Indeed, the detection of profenofos on the level of 0.025 ng/mL [174] or malathion on the level of 0.1 fM [168] does not have sense in terms of food safety or contamination assessment. To some extent, this also refers to the determination of some metabolites, such as trypthophan and urea.…”

Section: Other Carbon Nanomaterialsmentioning

confidence: 99%

Advances in Electrochemical Aptasensors Based on Carbon Nanomaterials

et al. 2020

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Carbon nanomaterials offer unique opportunities for the assembling of electrochemical aptasensors due to their high electroconductivity, redox activity, compatibility with biochemical receptors and broad possibilities of functionalization and combination with other auxiliary reagents. In this review, the progress in the development of electrochemical aptasensors based on carbon nanomaterials in 2016–2020 is considered with particular emphasis on the role of carbon materials in aptamer immobilization and signal generation. The synthesis and properties of carbon nanotubes, graphene materials, carbon nitride, carbon black particles and fullerene are described and their implementation in the electrochemical biosensors are summarized. Examples of electrochemical aptasensors are classified in accordance with the content of the surface layer and signal measurement mode. In conclusion, the drawbacks and future prospects of carbon nanomaterials’ application in electrochemical aptasensors are briefly discussed.

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Multi walled carbon nanotubes embedded conducting polymer based electrochemical aptasensor for estimation of malathion

Cited by 42 publications

References 30 publications

Conjugated Polymers for Aptasensing Applications

Conjugated Polymers for Aptasensing Applications

Multiple Recognition-Based Sensor for Pesticide Residues

Advances in Electrochemical Aptasensors Based on Carbon Nanomaterials

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