Multi-modal functional sensorless adaptive optics for small animal retinal imaging
Jun Song,
Yusi Miao,
Joanne A. Matsubara
et al.
Abstract:The proposed preclinical study investigates pathological characteristics of retinal diseases such as age-related macular degeneration (AMD) with transgenic small animal models using a multi-modal functional small animal retinal imaging system. For characterizing the animal models, we visualize the melanin concentration, lipofuscin accumulation, and choriocapillaris using a single imaging system. The system implements polarization-sensitive optical coherence tomography (PS-OCT), fluorescence scanning laser opht… Show more
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