Multi-core vesicle nanoparticles for controlled delivery of protein drug

Yuk, Soon Hong; Oh, Keun Sang; Kim, Seung Ki; Lee, Jin Ho; Cho, Sun Hang; Kim, Kwangmeyung; Jeon, Hyesung; Kwon, Ick Chan

doi:10.1007/s13233-012-0053-y

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Phospholipid-based Core/shell Nanoparticles1

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2013

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Cited by 2 publications

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“…The sustained release pattern of hGH was demonstrated with hGH-loaded core/shell NPs and the activity of loaded protein was preserved due to the presence of PEG. These results indicate that core/shell NPs with multi-cores can be utilized as a drug carrier for the sustained delivery of protein drugs [101].…”

Section: Phospholipid-based Core/shell Nanoparticlesmentioning

confidence: 82%

Core/Shell Nanoparticles for Drug Delivery and Diagnosis

Lee¹,

Kim²,

Lee³

et al. 2013

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

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Core/shell nanoparticles (NPs) are formed using various strategies and offer considerable advantages for diagnosis and therapy. Because of the hydrophilic nature of their shell with relatively small size, core/shell NPs have been utilized to solubilize hydrophobic drugs as well as imaging agents, improving pharmacokinetics. This chapter will introduce various types of core/shell NPs based on their preparation method and formation mechanism. The focus will be on the core/shell nanomedicine for tumor targeting, stimulated release of proteins, and cancer imaging capabilities.

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Section: Phospholipid-based Core/shell Nanoparticlesmentioning

confidence: 82%