Muciparous metaplasia and primary mucoepidermoid skin tumors

Zak, F. G.

doi:10.1001/archderm.100.1.23

Cited by 12 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Few mitoses are present. A lympho-histiocytic infiltrate surrounds the tumor lobule (3)(4)(5). Our case had this typical pattern, characterizing a low grade malignant tumor.…”

Section: Discussionsupporting

confidence: 51%

“…Despite this behavior, the tumor was classified as having "low grade" malignant potential by histologic criteria. Other tumors express only local aggressiveness (4,5). Our case, so far, has not recurred or metastasized.…”

Section: Landman and Farmermentioning

confidence: 45%

“…They are rare in other locations but have been described in bronchial mucosa (2) and ceruminous glands of the ear. In the skin, however, primary mucoepidermoid carcinomas are exceedingly rare (1,(3)(4)(5). We describe in this report a primary cutaneous mucoepidermoid carcinoma of the right ear.…”

mentioning

confidence: 81%

See 2 more Smart Citations

Primary cutaneous mucoepidermoid carcinoma: report of a case

Landman

Farmer

1991

J Cutan Pathol

View full text Add to dashboard Cite

Primary mucoepidermoid carcinomas of the skin are extremely rare tumors. We describe a primary cutaneous mucoepidermoid carcinoma arising in the right ear (posterior mid helix) of a 66-year-old white man. The tumor was 0.6 cm in diameter, ulcerated and nonencapsulated. No other tumors were found in the patient. Histologically the tumor showed the characteristics of a "low grade" mucoepidermoid carcinoma, consisting of lobules of polygonal cells with vesicular nuclei. In the center of the lobules were large vacuolated cells (goblet cells). Transitions between the two cell populations were present throughout the tumor. An epidermal attachment of the tumor, as well as epidermal dysplasia, predominantly at the acrosyringium was present, consistent with the theory of sweat duct histogenesis of these tumors. Immunoperoxidase staining showed positivity for epithelial membrane antigen, keratin and carcinoembryonic antigen. The latter was predominantly positive in the goblet cells. Cutaneous metastasis of mucoepidermoid carcinomas with epidermal attachment has been reported. Our case showed only ear involvement and follow-up at 8 months has revealed no evidence of recurrence. These findings are consistent with the diagnosis of primary cutaneous mucoepidermoid carcinoma.

show abstract

“…Few mitoses are present. A lympho-histiocytic infiltrate surrounds the tumor lobule (3)(4)(5). Our case had this typical pattern, characterizing a low grade malignant tumor.…”

Section: Discussionsupporting

confidence: 51%

Section: Landman and Farmermentioning

confidence: 45%

See 1 more Smart Citation

Primary cutaneous mucoepidermoid carcinoma: report of a case

Landman

Farmer

1991

J Cutan Pathol

View full text Add to dashboard Cite

show abstract

“…Although mucin-secreting glands are not a normal component of mature human skin, it has been noted by Zak & Palladino (1969) that muciparous cells and glatids do occur normally in the integument of fish, amphibians, and certain mammals. In man, single goblet cells are present in the epidermally-derived stratified squamous epithelium of the conjunctiva.…”

Section: Discussionmentioning

confidence: 99%

Adnexal Metaplasia in Carcinoma in situ of the Skin

1981

View full text Add to dashboard Cite

show abstract

“…This group has been ineluded by Mehregan et al (60) with the other eccrinc adenoeareinomas. It should be remembered that mncin may be seen in some solid-eystie hidradenomas (185).…”

Section: Mticinotis (Adenocystic) Carcinomamentioning

confidence: 99%

Eccrine tumors: a selective review

Weedon

1984

J Cutan Pathol

View full text Add to dashboard Cite

Muciparous metaplasia and primary mucoepidermoid skin tumors

Cited by 12 publications

References 0 publications

Primary cutaneous mucoepidermoid carcinoma: report of a case

Primary cutaneous mucoepidermoid carcinoma: report of a case

Adnexal Metaplasia in Carcinoma in situ of the Skin

Eccrine tumors: a selective review

Contact Info

Product

Resources

About