MRI Findings After Prostatic Artery Embolization for Treatment of Benign Hyperplasia

Frenk, Nathan E.; Baroni, Ronaldo Hueb; Carnevale, Francisco César; Gonçalves, O.D.; Antunes, Alberto A.; Srougi, Miguel; Cerri, Giovanni Guido

doi:10.2214/ajr.13.11692

Cited by 72 publications

(46 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several subsequent studies showed variable degrees of mean prostatic volume reduction from 18% to 32% [8, 14, 19, 20]. In the present study, there was a significant mean reduction of 28.1 mL (31.4%) in total prostatic volume and 17.8 mL (29.9%) in transition zone prostatic volume after PAE.…”

Section: Discussionsupporting

confidence: 64%

Comparison of Nonspherical Polyvinyl Alcohol Particles and Microspheres for Prostatic Arterial Embolization in Patients with Benign Prostatic Hyperplasia

Hwang

Park

Chang³

et al. 2017

BioMed Research International

View full text Add to dashboard Cite

Purpose To report early results following prostatic artery embolization (PAE) and compare outcomes between nonspherical polyvinyl alcohol (PVA) particles and microspheres to treat lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Methods PAE was performed in nine patients (mean age: 78.1 years) with symptomatic BPH. Embolization was performed using nonspherical PVA particles (250–355 μm) in four patients and microspheres (300–500 μm) in five patients. Results PAE was technically successful in all nine patients (100%). During a mean follow-up of 10.1 months, improvements in mean International Prostate Symptom Score (IPSS), Quality of Life (QoL), prostatic volume (total volume and transition zone), and peak urinary flow (Qmax) were 9.8 points, 2.3 points, 28.1 mL, 17.8 mL, and 4.5 mL/s, respectively. Clinical success was obtained in seven of nine patients (78%). Patients in the microsphere group showed greater improvement in IPSS, QoL, prostatic volume, and Qmax compared to patients in the nonspherical PVA particle group. However, significant difference was noted only in the prostatic volume. Conclusion PAE is a feasible, effective, and safe treatment option for BPH with LUTS. Use of microspheres showed greater prostatic volume reduction compared to nonspherical PVA particles.

show abstract

Section: Discussionsupporting

confidence: 64%

Comparison of Nonspherical Polyvinyl Alcohol Particles and Microspheres for Prostatic Arterial Embolization in Patients with Benign Prostatic Hyperplasia

Hwang

Park

Chang³

et al. 2017

BioMed Research International

View full text Add to dashboard Cite

show abstract

“…Frenk et al 8 reported that infarct areas were found in 70% of their series of 17 patients treated with PAE; nevertheless, 100% clinical success was achieved.…”

Section: Discussionmentioning

confidence: 96%

“…8,14 In analysing preembolisation MRI studies, many differences among prostates, in addition to their size, shape, or symmetry, have been described. 15,16 On T2-weighted MRI, different patterns of signal intensity can be observed, and these are certainly related to prostate tissue composition.…”

Section: Discussionmentioning

confidence: 99%

MRI assessment of prostatic ischaemia: best predictor of clinical success after prostatic artery embolisation for benign prostatic hyperplasia

Kisilevzky¹,

Faintuch

2016

Clinical Radiology

View full text Add to dashboard Cite

“…The presence of a cavity after thermal ablation is of clinical implication because of its positive correlation with an improvement in urinary performance and relief of outlet obstruction (40). In our previous studies with PAE in a DeKlerk’s model, various sizes of intraprostatic cavities were observed in all beagles 1 month after embolization (31); whereas it rarely occurred and was observed in only one out of eleven patients with BPH after prostatic artery embolization (41). Interestingly, our findings were inconsistent with a similar animal experiment by Brook et al (42).…”

Section: Hormone-induced Bph Modelsmentioning

confidence: 94%

Canine prostate models in preclinical studies of minimally invasive interventions: part II, benign prostatic hyperplasia models

Sun

Báez-Díaz

Sánchez‐Margallo

2017

Transl. Androl. Urol.

View full text Add to dashboard Cite

Canine prostate is widely used as animal model in the preclinical evaluation of emerging therapeutic interventions. Spontaneous benign prostatic hyperplasia (BPH) is common in adult intact male dogs with two distinct pathological types: glandular and complex form of prostatic hyperplasia. The complex form of prostatic hyperplasia, usually occurring in older dogs, represents an ideal model because of its unique pathologic feature, including not only glandular hyperplasia but also an increase in prostate stromal components. The limited commercial availability of adult dogs with spontaneous BPH motivates experimentally induced BPH in young dogs. Hormone-induced canine BPH model has been well established with various hormonal treatment regimens and administration approaches. The goal of this review is to provide the veterinary background in spontaneous BPH in dogs, summarize the techniques in hormonal induction of canine BPH, and highlight the pathological and clinical limitations of the canine models that may lead to distinct therapeutic responses compared to clinical trials in humans.

show abstract

MRI Findings After Prostatic Artery Embolization for Treatment of Benign Hyperplasia

Abstract: MRI can be used for assessing the development of infarcts and volume reduction in the prostate after embolization. Further studies are needed to correlate these findings to clinical outcome.

Cited by 72 publications

References 37 publications

Comparison of Nonspherical Polyvinyl Alcohol Particles and Microspheres for Prostatic Arterial Embolization in Patients with Benign Prostatic Hyperplasia

Comparison of Nonspherical Polyvinyl Alcohol Particles and Microspheres for Prostatic Arterial Embolization in Patients with Benign Prostatic Hyperplasia

MRI assessment of prostatic ischaemia: best predictor of clinical success after prostatic artery embolisation for benign prostatic hyperplasia

Canine prostate models in preclinical studies of minimally invasive interventions: part II, benign prostatic hyperplasia models

Contact Info

Product

Resources

About