MR imaging features of ventricular noncompaction: Emphasis on distribution and pattern of fibrosis

Left Ventricular Non-Compaction: Mid-myocardial Distribution of Late Gadolinium Enhancement in Compacted Segments

“…It was observed in both non-compacted and compacted segments with prevalence of compacted zones. This confirms the concept that LVNC is a diffuse process which includes both non-compacted and morphologically normal segments [11,16]. The pathophysiologic mechanisms leading to myocardial fibrosis in patients with LVNC remains unclear.…”

“…LGE (-) (n=4) P-value NC segments per patient 6.6 ± 1.6 6.8± 1. anterior and the lateral walls and that the septal segments are rarely affected by LVNC [6,11,12,14]. This may be explained by the normal compaction process that goes from base to apex, from epicardium to endocardium, and from the septal to the lateral wall.…”

“…Cardiovascular Magnetic Resonance (CMR) with Late Gadolinium Enhancement (LGE) is a proven method for detecting myocardial fibrosis [8]. Previous cardiac magnetic resonance imaging studies described the distribution of LGE in patients with isolated LVNC [7,[9][10][11] however, it still remains unclear. The purpose of this retrospective study is to describe the distribution of LGE in patients meeting cardiovascular magnetic resonance criteria for LVNC.…”

Cardiomyopathy mimicking left ventricular noncompaction in a patient with lupus nephritis

“…A ratio of noncompacted to compacted myocardium C2 was considered as a criteria of LVNC [3,7]. The affected myocardial segments are located in the apical, mid-lateral, and mid-inferior regions, and are often hypokinetic due to subendocardial hypoperfusion and microcirculatory dysfunction.…”

The Use of Contrast-Enhancement Cardiovascular Magnetic Resonance Imaging in Cardiomyopathies

“…According to Jacuier et al, a CMR-assessed trabeculated left ventricular mass above 20% of the global left ventricular mass is highly sensitive and specific for the diagnosis of left ventricular noncompaction. Right ventricular noncompaction which can be easily assessed with CMR, is reported in up to 60% op patients (Dursun et al, 2010). Recently, Dursun et al found that presence of CE (fibrosis) was found in 70% of the investigated patients with left ventricular noncompaction.…”