Mother-newborn separation at birth in hospitals: A possible risk for neurodevelopmental disorders?

Noémi, Császár-Nagy; Bókkon, István

doi:10.1016/j.neubiorev.2017.08.013

Cited by 52 publications

(33 citation statements)

References 255 publications

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“…The immediate newborn period is important for breastfeeding and maternal-infant bonding, and separation of mothers and infants during this time is a risk factor for maternal suicide 11 and child developmental problems. 10 Although there are cases in which custody loss among women with IDDs may be warranted, such as in instances of neglect or abuse, researchers suggest that many separations are preventable. 8,9 With our findings, we suggest that evidence-based interventions to avoid preventable maternal-infant separations at delivery and to support women who retain custody of their children after delivery are warranted, especially for women in the high-risk subgroups we identified.…”

Section: Discussionmentioning

confidence: 99%

“…8,9 Early infancy is critical for breastfeeding and bonding. 10 Separation of mothers and newborns has harmful effects, including increased risk of maternal suicide 11 and child developmental problems. 10 Yet, we know little about removal of newborns of women with IDDs.…”

mentioning

confidence: 99%

“…10 Separation of mothers and newborns has harmful effects, including increased risk of maternal suicide 11 and child developmental problems. 10 Yet, we know little about removal of newborns of women with IDDs. Researchers suggest that 40% to 60% of women with IDDs lose custody of their children at some point 12 -16 and that poverty, isolation, and mental illness increase risk of custody loss.…”

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confidence: 99%

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Maternal Intellectual or Developmental Disability and Newborn Discharge to Protective Services

et al. 2018

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BACKGROUND: Approximately half of women with intellectual and developmental disabilities (IDDs) lose custody of their children at some point in their child's development, but their rates of and risk factors for newborn discharge to child protective services from the birth hospitalization are relatively unknown. METHODS: We conducted a population-based study of newborns of 3845 women with IDDs and 379 834 women without IDDs in Ontario, Canada (2002-2012). We used modified Poisson regression to estimate adjusted relative risks (aRRs) and 95% confidence intervals (CIs) for discharge to child protective services directly from the birth hospitalization (1) comparing newborns of women with and without IDDs and (2) among newborns of women with IDDs according to sociodemographic, health, service, and perinatal characteristics. RESULTS: Approximately 5.7% of newborns of women with IDDs, compared with 0.2% of newborns of women without IDDs, were discharged to child protective services (aRR 8.10; 95% CI 6.51-10.09). Among newborns of women with IDDs, risk factors were maternal psychotic disorder (aRR 2.58; 95% CI 1.90-3.50), social assistance receipt (aRR 2.55; 95% CI 1.87-3.47), failure to receive an ultrasound by 20 weeks' gestation (aRR 1.76; 95% CI 1.32-2.34), and receipt of <4 prenatal visits by 36 weeks' gestation (aRR 1.71; 95% CI 1.05-2.78). CONCLUSIONS: Although women with IDDs are at risk for custody loss immediately postdelivery, certain subgroups are at higher risk than others. Women with vulnerabilities related to comorbid psychotic disorders, poverty, and inadequate prenatal care may benefit from tailored, behavior-based parenting interventions before and during pregnancy to prevent maternal-newborn separations.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Maternal Intellectual or Developmental Disability and Newborn Discharge to Protective Services

et al. 2018

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“…Animal experiments related to mother–infant attachment found that infant mice have neurobiological mechanisms that facilitate attachment and increased norepinephrine secretion, whereas the hypothalamic‐pituitary stress axis was inhibited. This way, parent–infant attachment is achieved, and infants can survive and be protected from danger (Csaszar‐Nagy & Bokkon, ; Perry et al, ).…”

Section: Introductionmentioning

confidence: 99%

Compassionate love, burnout and professional commitment in nurses

et al. 2020

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“…e significant discrepancy between the preclinical data and the clinical findings does not only relate to the inherent uncertainty to translate the experimental findings into humans but also relate to the confounding factors that weaken the powerfulness of the data from the preclinical research. Meanwhile, the confounding effect of early social stress in the clinical trials, such as maternal separation and social isolation or defeat [38][39][40][41], on the neurodevelopment possibly causes the discrepancy between preclinical and clinical studies. As it is beyond the scope of the present work, we do not discuss all of them in the present review.…”

Section: Introductionmentioning

confidence: 99%

General Anesthetic-Induced Neurotoxicity in the Immature Brain: Reevaluating the Confounding Factors in the Preclinical Studies

Luo

Tang

Zhao

et al. 2020

BioMed Research International

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General anesthetic (GA) is used clinically to millions of young children each year to facilitate surgical procedures, relieve perioperative stress, and provide analgesia and amnesia. During recent years, there is a growing concern regarding a causal association between early life GA exposure and subsequently long-term neurocognitive abnormalities. To address the increasing concern, mounting preclinical studies and clinical trials have been undergoing. Until now, nearly all of the preclinical findings show that neonatal exposure to GA causally leads to acute neural cell injury and delayed cognitive impairment. Unexpectedly, several influential clinical findings suggest that early life GA exposure, especially brief and single exposure, does not cause adverse neurodevelopmental outcome, which is not fully in line with the experimental findings and data from several previous cohort trials. As the clinical data have been critically discussed in previous reviews, in the present review, we try to analyze the potential factors of the experimental studies that may overestimate the adverse effect of GA on the developing brain. Meanwhile, we briefly summarized the advance in experimental research. Generally, our purpose is to provide some useful suggestions for forthcoming preclinical studies and strengthen the powerfulness of preclinical data.

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Mother-newborn separation at birth in hospitals: A possible risk for neurodevelopmental disorders?

Cited by 52 publications

References 255 publications

Maternal Intellectual or Developmental Disability and Newborn Discharge to Protective Services

Maternal Intellectual or Developmental Disability and Newborn Discharge to Protective Services

Compassionate love, burnout and professional commitment in nurses

General Anesthetic-Induced Neurotoxicity in the Immature Brain: Reevaluating the Confounding Factors in the Preclinical Studies

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