Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis

Chesnaye, Nicholas C.; Schaefer, Franz; Bonthuis, Marjolein; Holman, Rebecca; Baiko, Sergey; Baskın, Esra; Bjerre, Anna; Cloarec, Sylvie; Cornelissen, Elisabeth A.M.; Espinosa, Laura; Heaf, James; Stone, Rosário; Shtiza, Diamant; Zagożdżon, Ilona; Harambat, Jérôme; Jager, Kitty J.; Groothoff, Jaap W.; Stralen, Karlijn J. van

doi:10.1016/s0140-6736(17)30063-6

Cited by 50 publications

(35 citation statements)

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“…When it comes to survival on RRT, however, different patterns are seen in children and adults: higher expenditure on healthcare is associated with better survival on RRT for children [1] but poorer survival on RRT for adults [4]. While accepting the limitations of such high-level analyses, these findings do seem to suggest differences in the marginal gains from accepting individuals at the opposite extremes of age onto RRT programmes.…”

Section: Kidney Disease and Children -Optimising Care When Preventionmentioning

confidence: 92%

“…For some children, however, end-stage kidney disease (ESKD) cannot be avoided and its impact has to be managed and outcomes optimised. With increasing fiscal pressures on health services, the accompanying paper by Chesnaye and colleagues looking at macroeconomics and survival on RRT in Europe is very timely [1].…”

Section: Kidney Disease and Children -Optimising Care When Preventionmentioning

confidence: 99%

“…Furthermore, the comparison should ideally be between age-adjusted rates -France has an older age distribution (i.e. at lower risk) than the average (as demonstrated by the increase in hazard with adjustment for age in Figure 2 in [1]) and a lower RRT incidence rate compared with the UK (6.3 vs 9.8 per million of the population) [2]. We should also really be looking at outcomes for those with ESKD, rather than RRT which ignores outcomes in those who aren't accepted onto treatment.…”

Section: Kidney Disease and Children -Optimising Care When Preventionmentioning

confidence: 99%

See 2 more Smart Citations

Optimising care for children with kidney disease

Caskey

Morton

2017

The Lancet

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Section: Kidney Disease and Children -Optimising Care When Preventionmentioning

confidence: 92%

Section: Kidney Disease and Children -Optimising Care When Preventionmentioning

confidence: 99%

Section: Kidney Disease and Children -Optimising Care When Preventionmentioning

confidence: 99%

See 1 more Smart Citation

Optimising care for children with kidney disease

Caskey

Morton

2017

The Lancet

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“…1 The number of patients receiving renal replacement therapy (RRT) increased by 23% from 2006 to 2015. 2,3 Males predominate on dialysis. The mean age of patients receiving dialysis is 61.3 years, and 19% are over 80 years.…”

mentioning

confidence: 99%

“…5 Among children on dialysis, public health expenditure per country is inversely associated with mortality rates, ranging from 9.2 deaths per 1000 patient-years in France to 68.6 in Bulgaria. 2 Important inequities therefore persist. Regional perceptions that refugees and migrants impose high costs on health systems for RRT are unfounded.…”

mentioning

confidence: 99%

Challenges and opportunities for nephrology in Western Europe

Rondeau

Luyckx

Anders

et al. 2019

Kidney International

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Perinatal Diagnosis, Management, and Follow-up of Cystic Renal Diseases

et al. 2018

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IMPORTANCEPrenatal and neonatal cystic kidney diseases are a group of rare disorders manifesting as single, multiple unilateral, or bilateral cysts or with increased echogenicity of the renal cortex without macroscopic cysts. They may be accompanied by grossly enlarged kidneys, renal oligohydramnios, pulmonary hypoplasia, extrarenal abnormalities, and neonatal kidney failure. The prognosis is extremely variable from trivial to very severe or even uniformly fatal, which poses significant challenges to prenatal counseling and management.OBJECTIVE To provide a clinical practice recommendation for fetal medicine specialists, obstetricians, neonatologists, pediatric nephrologists, pediatricians, and human geneticists by aggregating current evidence and consensus expert opinion on current management of cystic nephropathies before and after birth.METHODS After 8 systematic literature reviews on clinically relevant questions were prepared (including 90 studies up to mid-2016), recommendations were formulated and formally graded at a consensus meeting that included experts from all relevant specialties. After further discussion, the final version was voted on by all members using the Delphi method. The recommendations were reviewed and endorsed by the working groups on inherited renal disorders of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and European Society for Paediatric Nephrology (ESPN); the German Society of Obstetrics and Gynecology (DGGG), German Society of Perinatal Medicine (DGPM), and German Society of Ultrasound in Medicine (DEGUM); and the alliance of patient organizations, PKD International. RECOMMENDATIONSThe group makes a number of recommendations on prenatal and postnatal imaging by ultrasound and magnetic resonance imaging, genetic testing, prenatal counseling, in utero therapeutic interventions, and postnatal management of prenatal and neonatal cystic kidney diseases, including provision of renal replacement therapy in neonates. In addition to detailed knowledge about possible etiologies and their prognosis, physicians need to be aware of recent improvements and remaining challenges of childhood chronic kidney disease, neonatal renal replacement therapy, and intensive pulmonary care to manage these cases and to empower parents for informed decision making.

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Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis

Cited by 50 publications

References 14 publications

Optimising care for children with kidney disease

Optimising care for children with kidney disease

Challenges and opportunities for nephrology in Western Europe

Perinatal Diagnosis, Management, and Follow-up of Cystic Renal Diseases

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