Nicolas Buchon, Dani Osman, Fabrice P.A. David, Hsiao Yu Fang, Jean-Philippe Boquete, Bart Deplancke, Bruno Lemaitre
Abstract:Although the gut is a central organ of Eumetazoans and is essential for organismal health, our understanding of its morphological and molecular determinants remains rudimentary. Here, we provide a comprehensive atlas of Drosophila adult midgut. Specifically, we uncover a fine-grained regional organization consisting of 14 subregions with distinct morphological, histological, and genetic properties. We also show that Drosophila intestinal regionalization is defined after adult emergence, remains stable througho…
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