Monoolein cubic phases containing hydrogen peroxide

Effect of cinnamic acid on phase transition and pH-dependent release property of monoolein cubic phase

“…It was reported that MO cubic phase undergoes the cubic-to-hexagonal phase transition when it is heated to a certain temperature. And the hexagonal phase is optically anisotropic and it exhibits a birefringence under the irradiation of polarized light [5,16]. Accordingly, it can be said that the phase transition of MO/CA(0) gel (pH 3.0) takes place around 59.5 8C.…”

“…The TEM photo of the MO/CA gel particles was taken on a transmission electron microscope (LEO 912AB OMEGA, Germany, located at Korea Basic Science and Institute (Chuncheon, South Korea)). The temperature-dependent phase transition of cubic phase was observed as described elsewhere [15,16]. An O-ring type of poly(ethylene terephthalate) film spacer (100 mm in thickness and 0.5 cm in inner diameter) was immobilized on a cover glass.…”

In vitro skin permeation of monoolein nanoparticles containing hydroxypropyl β-cyclodextrin/minoxidil complex

“…The degrees of MXD release from cubic phases were determined, following a method reported in a previous work (Choi et al, 2007;Kim et al, 2004). Distilled water of 5 ml, release medium, was laid over the cubic phases prepared using the saturation solution of MXD, and cubic phase (1.0%/0.32%), cubic phase (2.0%/0.44%), cubic phase (4.2%/0.66%), cubic phase (8.8%/1.12%) and cubic phase (19.4%/1.98%).…”

“…MO cubic phases containing either HP␤CD or HP␤CD/MXD complex were prepared based on a method reported in elsewhere (Choi et al, 2007;Kim et al, 2004). Two gram of MO contained in 20 ml vial were molten in a water bath of 60 • C. Either HP␤CD solutions (0%, 1.0%, 2.0%, 4.2%, 8.8%, 19.4%) or HP␤CD/MXD complex solutions (1.0%/0.32%, 2.0%/0.44%, 4.2%/0.66%, 8.8%/1.12%, 19.4%/1.98%) in distilled water were laid carefully on the molten MO so that the contents of aqueous solutions water in the mixtures are 30%.…”

Heterosídeos alcaloídicos de Solanum lycocarpum A. St.-Hil.: avaliação das atividades contra fungos dermatófitos e câncer de pele

“…A soma dos teores de SS e SM no extrato alcaloídico resultou em 89,46 %, o que demonstra que a extração seletiva ácido-base de tais compostos é bastante efetiva. No trabalho realizado por Kim et al (2004), uma formulação de fase cúbica também foi preparada contendo monoleína e apresentou separação de fases após 56 dias, tendo sido constatado por ressonância magnética nuclear de hidrogênio ( 1 H NMR) que o óleo que se formava com o tempo tratava-se da monoleína. Os resultados são expressos pela média ± erro padrão da média (E.P.M.)…”